PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 29109148-0 2017 HDAC8 substrate selectivity is determined by long- and short-range interactions leading to enhanced reactivity for full-length histone substrates compared with peptides. Peptides 160-168 histone deacetylase 8 Homo sapiens 0-5 16697640-1 2006 Peptides containing Nepsilon-thioacetyl-lysine and Nepsilon-acetyl-lysine were evaluated for their de(thio)acetylation catalyzed by human HDAC8 and SIRT1, two distinct protein deacetylases. Peptides 0-8 histone deacetylase 8 Homo sapiens 138-143 27459069-6 2016 Inspired by this, we tested the activity of HDAC8 using a variety of different acyl lysine peptides. Peptides 91-99 histone deacetylase 8 Homo sapiens 44-49