PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 24614212-6 2014 Our data revealed that MCT-induced PAH and right ventricular hypertrophy were associated with NF-kappaB activation, inflammatory response, and altered expression of bone morphogenetic protein receptor 2, inhibitor of differentiation, and Notch-3 signaling molecules in wild-type mice; and all these alterations were prevented in IkappaBalpha mutant mice treated with MCT. Monocrotaline 23-26 notch 3 Mus musculus 238-245 24614212-9 2014 We conclude that NF-kappaB regulates bone morphogenetic protein receptor 2-inhibitor of differentiation-Notch-3 axis genes and the subsequent endothelial cell apoptosis and endothelial-to-mesenchymal transition events in the lungs, providing new mechanistic information about MCT-induced PAH and right ventricular hypertrophy. Monocrotaline 276-279 notch 3 Mus musculus 104-111 24072692-3 2013 APPROACH AND RESULTS: Notch1, Notch3, Jagged1, and Herp2 protein were highly expressed in both the mouse model of hypoxia-induced PH and the rat model of monocrotaline-induced PH. Monocrotaline 154-167 notch 3 Mus musculus 30-36