PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
20060408-4	2010	We present for the first time, in vitro characterization of the effect of each component of Hsp70 system on alpha-synuclein (involved in Parkinson"s) using SEC and ThT assay.	tetrahydrothiophene	164-167	synuclein alpha	Homo sapiens	108-123	
31417259-5	2019	Results: ThT fluorescence spectroscopy revealed that ZVFe NPs shorten the lag phase and accelerate the fibrillation rate of alpha-synuclein.	tetrahydrothiophene	9-12	synuclein alpha	Homo sapiens	124-139	
28872299-4	2017	The aggregation kinetics of alpha-Syn using ThT fluorescence and conformational transition by circular dichroism (CD) in the presence and absence of these four compounds suggest that, except Quin, the remaining three molecules inhibit alpha-Syn aggregation in a concentration dependent manner.	tetrahydrothiophene	44-47	synuclein alpha	Homo sapiens	28-37	
27365127-6	2016	Turbidity, Rayleigh scattering analysis, Congo red assay and ThT measurements supported the TEM data i.e. the formation of fibrillar structure of human alpha-synuclein upon 12 h incubation.	tetrahydrothiophene	61-64	synuclein alpha	Homo sapiens	152-167	
25526628-2	2015	Compared with ThT, TPE-TPP shows a higher sensitivity in the detection of alpha-Syn oligomers as well as fibrils with a stronger fluorescence.	tetrahydrothiophene	14-17	synuclein alpha	Homo sapiens	74-83	
32870550-3	2020	To that end, we have designed and synthesized two naphthoquinone-dopamine-based hybrid small molecules, NQDA and Cl-NQDA, and demonstrated their ability to inhibit in vitro amyloid formation by alpha-Syn using ThT assay, CD, TEM, and Congo red birefringence.	tetrahydrothiophene	210-213	synuclein alpha	Homo sapiens	194-203