PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
1505915-0	1992	Differential effects of chenodeoxycholic and ursodeoxycholic acids on interleukin 1, interleukin 6 and tumor necrosis factor-alpha production by monocytes.	Ursodeoxycholic Acid	45-66	interleukin 6	Homo sapiens	85-130	
1639344-5	1992	Furthermore, ursodeoxycholic acid suppressed interleukin-2 and interleukin-4 production induced by concanavalin A and interferon-gamma production induced by polyinosinic-polycytidylic acid, but it did not affect interleukin-1 and interleukin-6 production induced by lipopolysaccharide in peripheral blood mononuclear cells.	Ursodeoxycholic Acid	13-33	interleukin 6	Homo sapiens	230-243	
34813629-9	2021	Ursodeoxycholate was previously reported to inhibit binding of SARS-CoV-2 to angiotensin-converting enzyme 2; suppress pro-inflammatory cytokines like TNF-alpha, IL-1beta, IL-2, IL-4, and IL-6; have antioxidant and anti-apoptotic effects; and increase alveolar fluid clearance in acute respiratory distress syndrome.	Ursodeoxycholic Acid	0-16	interleukin 6	Homo sapiens	188-192	
31960968-9	2020	RESULTS: We report here that UDCA significantly reduced the IL1beta and TNFalpha-induced expression of IL1, IL6 and IL8 in gingival fibroblasts and the HSC-2 cell line.	Ursodeoxycholic Acid	29-33	interleukin 6	Homo sapiens	108-111	
31960968-10	2020	In RAW 264.7 macrophages, UDCA attenuated the expression of IL1alpha, IL1beta and IL6 that was increased by saliva.	Ursodeoxycholic Acid	26-30	interleukin 6	Homo sapiens	82-85	
31960968-11	2020	Immunoassay confirmed the capacity of UDCA to reduce inflammation-induced production of IL6 in gingival fibroblasts, HSC-2 and RAW 264.7 cells.	Ursodeoxycholic Acid	38-42	interleukin 6	Homo sapiens	88-91