PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
27630169-6	2016	In wild-type hepatic macrophages, deoxycholic acid induced the association of Gal3 and NLRP3 with direct activation of the inflammasome, resulting in an increase in IL-1beta.	Deoxycholic Acid	34-50	interleukin 1 beta	Mus musculus	165-173	
27965665-4	2016	Here, we, for the first time, showed that DCA dose-dependently induced NLRP3 inflammasome activation and highly pro-inflammatory cytokine-IL-1beta production in macrophages.	Deoxycholic Acid	42-45	interleukin 1 beta	Mus musculus	138-146	
27965665-6	2016	Colorectal instillation of DCA significantly increased mature IL-1beta level in colonic tissue and exacerbated DSS-induced colitis, while in vivo blockage of NLRP3 inflammasome or macrophage depletion dramatically reduced the mature IL-1beta production and ameliorated the aggravated inflammatory injury imposed by DCA.	Deoxycholic Acid	27-30	interleukin 1 beta	Mus musculus	62-70	
27965665-6	2016	Colorectal instillation of DCA significantly increased mature IL-1beta level in colonic tissue and exacerbated DSS-induced colitis, while in vivo blockage of NLRP3 inflammasome or macrophage depletion dramatically reduced the mature IL-1beta production and ameliorated the aggravated inflammatory injury imposed by DCA.	Deoxycholic Acid	27-30	interleukin 1 beta	Mus musculus	233-241