PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 22108623-0 2011 2-Hydroxy-3-methylanthraquinone from Hedyotis diffusa WILLD induces apoptosis via alteration of Fas/FasL and activation of caspase-8 in human leukemic THP-1 cells. 2-hydroxy-3-methylanthraquinone 0-31 Fas ligand Homo sapiens 100-104 22108623-3 2011 The current study determines the role of Fas/FasL in THP-1 cell apoptosis induced by 2-hydroxy-3-methylanthraquinone from H. diffusa. 2-hydroxy-3-methylanthraquinone 85-116 Fas ligand Homo sapiens 45-49 22108623-10 2011 CONCLUSIONS: For the first time, our study suggests that 2-hydroxy-3-methylanthraquinone from H. diffusa is able to enhance apoptosis of THP-1 cells, at least in part, through activation of Fas/FasL, DR4 and TRAIL. 2-hydroxy-3-methylanthraquinone 57-88 Fas ligand Homo sapiens 194-198