PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
32305165-2	2020	Among the synthesized surrogates of isoxazole and pyrazole, compounds 4a, 5e and 12b exhibited potent Hsp90 inhibition in ATPase activity and Her2 degradation assays and significant antitumor activity in A2780 and HCT116 cell lines.	Isoxazoles	36-45	erb-b2 receptor tyrosine kinase 2	Homo sapiens	142-146	
31513003-0	2019	In-silico Design, ADMET Screening, MM-GBSA Binding Free Energy of Some Novel Isoxazole Substituted 9-Anilinoacridines as HER2 Inhibitors Targeting Breast Cancer.	Isoxazoles	77-86	erb-b2 receptor tyrosine kinase 2	Homo sapiens	121-125	
31513003-4	2019	OBJECTIVE: Some novel isoxazole substituted 9-anilinoacridines(1a-z) were designed by in-silico technique for their HER2 inhibitory activity.	Isoxazoles	22-31	erb-b2 receptor tyrosine kinase 2	Homo sapiens	116-120	
31513003-12	2019	CONCLUSION: The outcomes reveal that this study provides evidence for the consideration of isoxazole substituted 9-aminoacridine derivatives as potential HER2 inhibitors.	Isoxazoles	91-100	erb-b2 receptor tyrosine kinase 2	Homo sapiens	154-158