PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 27124646-2 2016 Curcumin is a potential anticancer agent with p-glycoprotein (p-gp) inhibiting activity may be co-administered with docetaxel as a nanosuspension to enhance its anticancer effect by increasing the oral bioavailability and decreasing drug efflux. Curcumin 0-8 phosphoglycolate phosphatase Mus musculus 46-60 18006147-3 2008 Here, we demonstrate that curcumin down-regulates P-gp expression in multidrug-resistant L1210/Adr cells. Curcumin 26-34 phosphoglycolate phosphatase Mus musculus 50-54 18006147-7 2008 Thus, curcumin can contribute to the reversal of the MDR phenotype, probably due to the suppression of P-gp expression via the inhibition of the PI3K/Akt/NF-kappa B signaling pathway. Curcumin 6-14 phosphoglycolate phosphatase Mus musculus 103-107 27124646-2 2016 Curcumin is a potential anticancer agent with p-glycoprotein (p-gp) inhibiting activity may be co-administered with docetaxel as a nanosuspension to enhance its anticancer effect by increasing the oral bioavailability and decreasing drug efflux. Curcumin 0-8 phosphoglycolate phosphatase Mus musculus 62-66 27124646-10 2016 CONCLUSIONS: The in vitro and in vivo study of the nanosuspensions has shown that Co-administration of Curcumin as a p-gp inhibitor with docetaxel may have the potential to increase the anti-breast cancer efficacy of both drugs. Curcumin 103-111 phosphoglycolate phosphatase Mus musculus 117-121