PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
34611905-4	2022	RESULTS: The encapsulation efficiency of curcumin was found to depend on LSP concentration and was highest (86.32%, w/w) at 50 mg mL-1 .	Curcumin	41-49	L1 cell adhesion molecule	Mus musculus	130-134	
34060984-9	2021	Nanoliposomal curcumin inhibitory concentration (IC50) at hours 24, 48, and 72 were 6.41, 3.8, and 2.33 microg mL-1, respectively.	Curcumin	14-22	L1 cell adhesion molecule	Mus musculus	111-115	
35166283-6	2022	Furthermore, the antioxidant and acetylcholinesterase (AChE) inhibitory activities of the recovered curcumin were evaluated, with IC50 values of 25.58 +- 0.51 and 19.12 +- 0.83 mug mL-1, respectively.	Curcumin	100-108	L1 cell adhesion molecule	Mus musculus	181-185	
31799527-5	2020	This system was able to encapsulate curcumin at 80 mug mL-1 with an efficiency of ca.	Curcumin	36-44	L1 cell adhesion molecule	Mus musculus	55-59	
32435141-8	2020	The method was linear between 44 and 261 ng mL-1, showing intra-day (2.05.6%) and inter-day (4.0-5.1%) precision with accuracy and selectiveness (curcumin tR = 8.7 min and internal standard tR = 13.9 min with relative recovery of 83.2%).	Curcumin	146-154	L1 cell adhesion molecule	Mus musculus	44-48	
33298267-4	2021	This method allows for the determination of curcumin in the range of 0.1-10 mug mL-1 and the detection limit is 21 ng mL-1.	Curcumin	44-52	L1 cell adhesion molecule	Mus musculus	80-84	
33298267-4	2021	This method allows for the determination of curcumin in the range of 0.1-10 mug mL-1 and the detection limit is 21 ng mL-1.	Curcumin	44-52	L1 cell adhesion molecule	Mus musculus	118-122	
33250162-4	2021	Under these conditions, four curcuminoids including curcumin, demethoxy curcumin (DMC), bisdemethoxy curcumin (BDMC) and demethyl curcumin (DEC) could be well separated within 18 min, and the detection limits (LOD, based on S/N=3) were calculated to be 71, 60, 22, and 147 pg mL-1, respectively.	Curcumin	29-37	L1 cell adhesion molecule	Mus musculus	276-280	
32676763-7	2020	The sensitivity of the described method in terms of detection limits was 0.3 and 0.1 mug mL-1 for curcumin and nanocurcumin, respectively.	Curcumin	98-106	L1 cell adhesion molecule	Mus musculus	89-93	
31945443-6	2020	Also, beta-CD/CUR-MBN exerted a prolonged cytotoxic effect (up to 96 h), even using a low concentration (50 mug mL-1), indicating that the curcumin in the polymeric membrane showed increased bioavailability under the tested condition.	Curcumin	139-147	L1 cell adhesion molecule	Mus musculus	112-116	
31468672-5	2019	The results reveal that curcumin possesses insignificant inhibitory activity against EV71 infection in RD cells [half-maximal effective concentration (EC50 ) >200 microg mL-1 ] but exhibits high cytotoxicity toward RD cells (half-maximal cytotoxic concentration (CC50 ) <13 microg mL-1 ).	Curcumin	24-32	L1 cell adhesion molecule	Mus musculus	173-177	
31468672-5	2019	The results reveal that curcumin possesses insignificant inhibitory activity against EV71 infection in RD cells [half-maximal effective concentration (EC50 ) >200 microg mL-1 ] but exhibits high cytotoxicity toward RD cells (half-maximal cytotoxic concentration (CC50 ) <13 microg mL-1 ).	Curcumin	24-32	L1 cell adhesion molecule	Mus musculus	287-291	
31468672-6	2019	The EC50 (0.2 microg mL-1 ) and CC50 (452.2 microg mL-1 ) of Cur-CQDs are >1000-fold lower and >34-fold higher, respectively, than those of curcumin, demonstrating their far superior antiviral capabilities and high biocompatibility.	Curcumin	146-154	L1 cell adhesion molecule	Mus musculus	51-55	
31494752-7	2019	Based on this, a fluorometric assay with a detection limit of 21 ng mL-1 was developed for the determination of curcumin.	Curcumin	112-120	L1 cell adhesion molecule	Mus musculus	68-72	
31432995-2	2019	METHODS: The rats underwent ACLT and received 50mul of curcumin at the concentration of 1 mg mL-1 and 10 mug LPS by intra-articular injection once a week for 8 weeks.	Curcumin	55-63	L1 cell adhesion molecule	Mus musculus	93-104	
27383887-7	2016	The inhibition of cell growth by curcumin (IC50 = 41.69 +- 2.87 mug mL-1) was much more effective than that of methanolic extract (IC50 = 196.12 +- 5.25 mug mL-1).	Curcumin	33-41	L1 cell adhesion molecule	Mus musculus	68-72	
27383887-7	2016	The inhibition of cell growth by curcumin (IC50 = 41.69 +- 2.87 mug mL-1) was much more effective than that of methanolic extract (IC50 = 196.12 +- 5.25 mug mL-1).	Curcumin	33-41	L1 cell adhesion molecule	Mus musculus	157-161	
31184357-1	2019	We report a one-step emulsification and rapid freeze-drying process to develop a curcumin-ionic liquid (CCM-IL) complex that could be readily dispersed in water with a significantly enhanced solubility of ~8 mg mL-1 and half-life (t1/2) of ~260 min compared with free CCM (solubility ~30 nM and t1/2 ~ 20 min).	Curcumin	81-89	L1 cell adhesion molecule	Mus musculus	211-215	
29727780-6	2018	The linear calibration range for the method was 2.50-500 ng mL-1 for curcumin, COG, and COS.	Curcumin	69-77	L1 cell adhesion molecule	Mus musculus	60-64