PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
31998463-4	2019	The present study aimed to compare cyclin D1 (CCN D1) gene expression in hepatocellular carcinoma cell line (HUH7) when it is treated with nanomicelle curcumin and sorafenib.	Curcumin	151-159	MIR7-3 host gene	Homo sapiens	109-113	
31998463-10	2019	The finding of this study revealed that, in comparison to sorafenib alone, the treatment of HUH7 with a nanomicelle curcumin IC50 dose, in combination with sorafenib, might down-regulate CCN D1 gene expression.	Curcumin	116-124	MIR7-3 host gene	Homo sapiens	92-96	
31998463-6	2019	Materials and Methods: The toxic dose (IC50) of nanomicelle curcumin and sorafenib were detected after treatment of HUH7 cell lines with different dose of mentioned agents followed by MTT assay.	Curcumin	60-68	MIR7-3 host gene	Homo sapiens	116-120	
31592057-0	2019	Curcumin may induce lipolysis via proteo-stress in Huh7 human hepatoma cells.	Curcumin	0-8	MIR7-3 host gene	Homo sapiens	51-55	
31592057-3	2019	In this study, we found that curcumin or heat shock treatment up-regulated the expression of adipose triglyceride lipase (ATGL) in Huh7 hepatoma cells, which resulted in acceleration of lipolysis.	Curcumin	29-37	MIR7-3 host gene	Homo sapiens	131-135	
29615146-1	2018	The aim of this study is to investigate the pharmacological effect of curcumin on hepatocellular carcinoma (HCC) Huh7 and PLC cells and to explore its mechanism in the pathological process by screening possible target genes.	Curcumin	70-78	MIR7-3 host gene	Homo sapiens	113-117	
29615146-2	2018	MTT assay was used to detect the effect of curcumin on the growth of Huh7 and PLC cells.	Curcumin	43-51	MIR7-3 host gene	Homo sapiens	69-73	
29615146-4	2018	Flow cytometry indicated that curcumin could significantly accelerate apoptosis of Huh7 and PLC cells, showing an obvious dosage effect.	Curcumin	30-38	MIR7-3 host gene	Homo sapiens	83-87	
21351482-1	2009	The effect of curcumin on JAK-STAT signaling pathway was investigated in hepatoma cell lines Huh7 and Hep3B.	Curcumin	14-22	MIR7-3 host gene	Homo sapiens	93-97	
27234697-9	2016	Annexin-V-PI test showed curcumin-induced apoptosis was enhanced in Huh7 as well as HepG2, compared to untreated cells.	Curcumin	25-33	MIR7-3 host gene	Homo sapiens	68-72	
21078213-2	2011	Using a luciferase reporter gene assay, we tested curcumin for its ability to induce PON1 in Huh7 hepatocytes in culture.	Curcumin	50-58	MIR7-3 host gene	Homo sapiens	93-97	
21078213-3	2011	Curcumin ( >= 10 mumol/l) dose-dependently induced PON1 transactivation in Huh7 cells.	Curcumin	0-8	MIR7-3 host gene	Homo sapiens	78-82	
21351482-2	2009	Curcumin inhibited cell proliferation and induced apoptosis of both cell lines, but Huh7 cells were more sensitive to curcumin than Hep3B cells.	Curcumin	118-126	MIR7-3 host gene	Homo sapiens	84-88	
21351482-3	2009	Curcumin (50 micromol x L(-1)) significantly increased phosphorylations of p38 (T180/Y182) and STAT-1 (S727) in Huh7 and Hep3B cells, and caused relocalization of phosphorylated-STAT-1 (Y701) from cytoplasm to nucleus in Hep3B cells.	Curcumin	0-8	MIR7-3 host gene	Homo sapiens	112-116	
21351482-4	2009	In addition, curcumin (25 and 50 micromol x L(-1)) dramatically suppressed the phosphorylation level of STAT-1 (Y701) and resulted in a significant reduction of nuclear phosphorylated-STAT-1 (Y701) in Huh7 cells.	Curcumin	13-21	MIR7-3 host gene	Homo sapiens	201-205