PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 32290922-1 2020 OBJECTIVE: To study the effect of curcumin on the expression of glucose regulated protein 78 kD(GRP78) and cysteinyl aspartate specific proteinase-12(caspase-12) of myocardial endoplasmic reticulum stress related factors in type 2 diabetes rats. Curcumin 34-42 heat shock protein family A (Hsp70) member 5 Rattus norvegicus 96-101 19513510-10 2009 Curcumin also induced endoplasmic reticulum stress in N18 cells which was based on the changes of GADD153 and GRP78 and caused Ca2+ release. Curcumin 0-8 heat shock protein family A (Hsp70) member 5 Rattus norvegicus 110-115 32290922-11 2020 Compared with model group, FBG and LDH levels and HWI were reduced, the collagen fiber of intercellular space were decreased, the protein expression levels of GRP78 and caspase-12 were lowered in high dose of curcumin group(P<0. Curcumin 209-217 heat shock protein family A (Hsp70) member 5 Rattus norvegicus 159-164 30859861-5 2019 Curcumin attenuated PA-induced reduction in cell viability and activation of apoptosis, Caspase 3 activity, BAX, CHOP, and GRP78 expression. Curcumin 0-8 heat shock protein family A (Hsp70) member 5 Rattus norvegicus 123-128 30859861-7 2019 Both curcumin and 4-PBA also attenuated PA-induced increase in ER stress protein (CHOP and GRP78) expression. Curcumin 5-13 heat shock protein family A (Hsp70) member 5 Rattus norvegicus 91-96 30968152-16 2019 Furthermore, curcumin abolished NF-kappaB signal transduction and protected the cells from CPT-11-induced apoptosis by upregulating the expression of molecular chaperones, such as GRP78, P4HB and PRDX4, and suppressing the levels of the apoptosis-related proteins, CHOP and cleaved caspase-3. Curcumin 13-21 heat shock protein family A (Hsp70) member 5 Rattus norvegicus 180-185 29065403-6 2017 RESULTS: Our results indicated that Curcumin-NP reversed oxidative stress, growth inhibition and cell apoptosis accompanied with down-regulation of apoptotic markers Caspase-3 and GRP-78 in vitro. Curcumin 36-44 heat shock protein family A (Hsp70) member 5 Rattus norvegicus 180-186 29065403-8 2017 In addition, kidney tissues from Curcumin-NP-treated AKI rats exhibited reduced oxidative stress, apoptosis, and cleaved Capase-3 and GRP-78 expression. Curcumin 33-41 heat shock protein family A (Hsp70) member 5 Rattus norvegicus 134-140 31223428-5 2019 Curcumin inhibited the expression of cleaved caspase3, cleaved poly (ADP-ribose) polymerase (PARP), C/EBP homologous protein (CHOP), and glucose-regulated protein78 (GRP78) and upregulated the chondroprotective protein Bcl2 in TBHP-treated chondrocytes. Curcumin 0-8 heat shock protein family A (Hsp70) member 5 Rattus norvegicus 137-164 31223428-5 2019 Curcumin inhibited the expression of cleaved caspase3, cleaved poly (ADP-ribose) polymerase (PARP), C/EBP homologous protein (CHOP), and glucose-regulated protein78 (GRP78) and upregulated the chondroprotective protein Bcl2 in TBHP-treated chondrocytes. Curcumin 0-8 heat shock protein family A (Hsp70) member 5 Rattus norvegicus 166-171