PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
34237276-0	2021	DRD3-dependent plasticity within the VP drives subcircuit activity critical for cocaine seeking.	Cocaine	80-87	dopamine receptor D3	Homo sapiens	0-4	
12893467-2	1996	The dopamine D3 receptor (genetic locus DRD3) is localized to brain regions that have been implicated in the reinforcing effects of a number of substances of abuse, including cocaine.	Cocaine	175-182	dopamine receptor D3	Homo sapiens	40-44	
12893467-5	1996	We examined alleles of the DRD3 gene in cocaine dependence using a genetic association strategy in samples of 62 white and 62 black cocaine-dependent individuals.	Cocaine	40-47	dopamine receptor D3	Homo sapiens	27-31	
12893467-5	1996	We examined alleles of the DRD3 gene in cocaine dependence using a genetic association strategy in samples of 62 white and 62 black cocaine-dependent individuals.	Cocaine	132-139	dopamine receptor D3	Homo sapiens	27-31	
34237276-4	2021	(2021) demonstrate how cocaine induces circuit-specific changes within the VP via dopamine-receptor-D3-dependent processes to promote cocaine seeking.	Cocaine	23-30	dopamine receptor D3	Homo sapiens	82-102	
34237276-4	2021	(2021) demonstrate how cocaine induces circuit-specific changes within the VP via dopamine-receptor-D3-dependent processes to promote cocaine seeking.	Cocaine	134-141	dopamine receptor D3	Homo sapiens	82-102	
18790725-2	2008	We review recent studies of the effects of Drd3 antagonists or partial agonists on the control of self-administration of intravenous (IV) cocaine, IV morphine and oral ethanol on reward-rich and lean schedules, in reinstatement tests, on second-order schedules and on the acquisition and expression of conditioned place preference (CPP) and conditioned motor activity.	Cocaine	138-145	dopamine receptor D3	Homo sapiens	43-47	
34048697-0	2021	Ventral pallidum DRD3 potentiates a pallido-habenular circuit driving accumbal dopamine release and cocaine seeking.	Cocaine	100-107	dopamine receptor D3	Homo sapiens	17-21	
34048697-3	2021	Here, we demonstrate that dopamine receptor D3 (DRD3)-dependent plasticity in the ventral pallidum (VP) drives potentiation of dopamine release in the nucleus accumbens during relapse to cocaine seeking after abstinence.	Cocaine	187-194	dopamine receptor D3	Homo sapiens	26-46	
34048697-3	2021	Here, we demonstrate that dopamine receptor D3 (DRD3)-dependent plasticity in the ventral pallidum (VP) drives potentiation of dopamine release in the nucleus accumbens during relapse to cocaine seeking after abstinence.	Cocaine	187-194	dopamine receptor D3	Homo sapiens	48-52	
34048697-4	2021	We show that two distinct VP DRD3+ neuronal populations projecting to either the lateral habenula (LHb) or the ventral tegmental area (VTA) display different patterns of activity during drug seeking following abstinence from cocaine self-administration and that selective suppression of elevated activity or DRD3 signaling in the LHb-projecting population reduces drug seeking.	Cocaine	225-232	dopamine receptor D3	Homo sapiens	29-33	
18790725-6	2008	Drd3 agents also block the ability of conditioned cues to reinstate responding for cocaine or food.	Cocaine	83-90	dopamine receptor D3	Homo sapiens	0-4	
12589386-0	2003	Attenuation of cue-controlled cocaine-seeking by a selective D3 dopamine receptor antagonist SB-277011-A.	Cocaine	30-37	dopamine receptor D3	Homo sapiens	61-81	
10523822-0	1999	Homozygosity at the dopamine DRD3 receptor gene in cocaine dependence.	Cocaine	51-58	dopamine receptor D3	Homo sapiens	29-33	
10523822-1	1999	We examined the hypothesis that the dopamine D3 receptor gene (DRD3) is a susceptibility factor for cocaine dependence.	Cocaine	100-107	dopamine receptor D3	Homo sapiens	63-67	
10523822-2	1999	The MscI/BalI polymorphism of the DRD3 gene was examined in 47 Caucasian subjects with cocaine dependence and 305 Caucasian controls.	Cocaine	87-94	dopamine receptor D3	Homo sapiens	34-38	
10523822-6	1999	The DRD3 gene accounted for 1.64% of the variance of cocaine dependence.	Cocaine	53-60	dopamine receptor D3	Homo sapiens	4-8	
10523822-8	1999	These findings support a modest role of the DRD3 gene in susceptibility to cocaine dependence.	Cocaine	75-82	dopamine receptor D3	Homo sapiens	44-48