PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 23415012-7 2013 Western blot analysis showed that SNS-032 strongly inhibited the phosphorylation of mammalian target of rapamycin (mTOR) on Ser 2448 and Ser2481, and that removal of SNS-032 resulted in partial recovery of cell death and reactivation of phosphorylation of mTOR. Tin 34-37 mechanistic target of rapamycin kinase Homo sapiens 84-113 23415012-7 2013 Western blot analysis showed that SNS-032 strongly inhibited the phosphorylation of mammalian target of rapamycin (mTOR) on Ser 2448 and Ser2481, and that removal of SNS-032 resulted in partial recovery of cell death and reactivation of phosphorylation of mTOR. Tin 34-37 mechanistic target of rapamycin kinase Homo sapiens 115-119 23415012-7 2013 Western blot analysis showed that SNS-032 strongly inhibited the phosphorylation of mammalian target of rapamycin (mTOR) on Ser 2448 and Ser2481, and that removal of SNS-032 resulted in partial recovery of cell death and reactivation of phosphorylation of mTOR. Tin 34-37 mechanistic target of rapamycin kinase Homo sapiens 256-260 32178401-6 2020 RESULTS: CAP treatment increased the temperature and pH of the media, while its combination with SN resulted in a decrease in intracellular ATP with the downregulation of PI3K/AKT/mTOR survival and RAS/MEK transcriptional pathways. Tin 97-99 mechanistic target of rapamycin kinase Homo sapiens 180-184 35504052-15 2022 CONCLUSION: SN significantly inhibits NPC cells proliferation and metastasis in vitro and in vivo via selectively inhibit Grp94 and then blocking PI3K/AKT/mTOR/HIF-1alpha signaling pathway. Tin 12-14 mechanistic target of rapamycin kinase Homo sapiens 155-159 32178401-9 2020 CONCLUSION: CAP and SN together activate autophagy in G-361 cells by activating PI3K/mTOR and EGFR pathways, expressing autophagy-related transcription factors and genes. Tin 20-22 mechanistic target of rapamycin kinase Homo sapiens 85-89