PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
19959817-4	2010	The increase was reduced by the p38 MAP kinase (p38) inhibitor SB203580, by the cytosolic phospholipase A2 (cPLA(2)) inhibitor AACOCF3, and by the lyso-PAF acetyltransferase inhibitor sanguinarin, indicating that capsaicin-induced PAF production may be mediated by activation of cPLA(2), p38, and lyso-PAF acetyltransferase.	sanguinarine	184-195	mitogen-activated protein kinase 14	Homo sapiens	48-51	
19959817-4	2010	The increase was reduced by the p38 MAP kinase (p38) inhibitor SB203580, by the cytosolic phospholipase A2 (cPLA(2)) inhibitor AACOCF3, and by the lyso-PAF acetyltransferase inhibitor sanguinarin, indicating that capsaicin-induced PAF production may be mediated by activation of cPLA(2), p38, and lyso-PAF acetyltransferase.	sanguinarine	184-195	mitogen-activated protein kinase 14	Homo sapiens	32-46	
19959817-4	2010	The increase was reduced by the p38 MAP kinase (p38) inhibitor SB203580, by the cytosolic phospholipase A2 (cPLA(2)) inhibitor AACOCF3, and by the lyso-PAF acetyltransferase inhibitor sanguinarin, indicating that capsaicin-induced PAF production may be mediated by activation of cPLA(2), p38, and lyso-PAF acetyltransferase.	sanguinarine	184-195	mitogen-activated protein kinase 14	Homo sapiens	32-35	
30942394-11	2019	Sanguinarine also significantly increased the phosphorylation levels of c-Jun N-terminal kinase and p38, which indicated the involvement of the mitogen-activated protein kinase signaling pathway.	sanguinarine	0-12	mitogen-activated protein kinase 14	Homo sapiens	100-103	
24649171-5	2013	Sanguinarine also inhibited the VEGF-mediated Akt and p38 activation, as well as VE-cadherin protein phosphorylation.	sanguinarine	0-12	mitogen-activated protein kinase 14	Homo sapiens	54-57	
20208361-0	2010	Sanguinarine as a potent and specific inhibitor of protein phosphatase 2C in vitro and induces apoptosis via phosphorylation of p38 in HL60 cells.	sanguinarine	0-12	mitogen-activated protein kinase 14	Homo sapiens	128-131	
20208361-3	2010	In vivo, sanguinarine showed cytotoxicity toward human promyelocytic leukemia cell line HL60, with an IC(50) value of 0.37 microM, and induced apoptosis through a caspase-3/7-dependent mechanism involving the phosphorylation of p38, a PP2Calpha substrate.	sanguinarine	9-21	mitogen-activated protein kinase 14	Homo sapiens	228-231	
20208361-4	2010	The apoptosis activity induced by sanguinarine was partially inhibited by a p38 inhibitor, SB203580, and was involved in the phospho-p38 protein in HL60 cells.	sanguinarine	34-46	mitogen-activated protein kinase 14	Homo sapiens	76-79	
20208361-4	2010	The apoptosis activity induced by sanguinarine was partially inhibited by a p38 inhibitor, SB203580, and was involved in the phospho-p38 protein in HL60 cells.	sanguinarine	34-46	mitogen-activated protein kinase 14	Homo sapiens	133-136