PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 15299076-9 2004 Immunoblot analysis showed that sanguinarine treatment of both LNCaP and DU145 cells resulted in significant (1) induction of cyclin kinase inhibitors p21/WAF1 and p27/KIP1; (2) down-regulation of cyclin E, D1, and D2; and (3) down-regulation of cyclin-dependent kinase 2, 4, and 6. sanguinarine 32-44 cyclin dependent kinase 2 Homo sapiens 246-281