PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 29783958-0 2018 Sanguinarine triggers intrinsic apoptosis to suppress colorectal cancer growth through disassociation between STRAP and MELK. sanguinarine 0-12 maternal embryonic leucine zipper kinase Homo sapiens 120-124 29783958-16 2018 Sanguinarine dephosphorylated STRAP and MELK and disrupted the association between them in HCT116 and SW480 cells. sanguinarine 0-12 maternal embryonic leucine zipper kinase Homo sapiens 40-44 29783958-17 2018 The expression and association between STRAP and MELK were also attenuated by sanguinarine in the tumor tissues. sanguinarine 78-90 maternal embryonic leucine zipper kinase Homo sapiens 49-53 29783958-20 2018 CONCLUSIONS: Sanguinarine dephosphorelates STRAP and MELK and disassociates the interaction between them to trigger intrinsic apoptosis. sanguinarine 13-25 maternal embryonic leucine zipper kinase Homo sapiens 53-57