PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 11502101-1 2001 The apoptosis related proteins Bax, Bcl-2, and NF-kappaB were analyzed in sanguinarine induced apoptosis and blister cell death (BCD) of K562 erythroleukemia cells and in sanguinarine treated high Bcl-2 expressing JM1 pre-B lymphoblastic cells, utilizing immunofluorescence-flow cytometry. sanguinarine 74-86 coiled-coil domain containing 22 Homo sapiens 214-217 11502101-3 2001 In contrast, high Bcl-2 expressing JM1 cells, when exposed to the same concentrations (and duration) of sanguinarine that induced PCD and BCD in K562 cells, failed to show the respective morphologies while showing a concomitant increase in Bcl-2. sanguinarine 104-116 coiled-coil domain containing 22 Homo sapiens 35-38 11787859-2 2001 We previously demonstrated that sanguinarine treatment at a low level induced apoptosis or programmed cell death (PCD) in the Bcl-2 low-expressing K562 human erythroleukemia cells, and that a high level induced blister cell death (BCD); whereas Bcl-2 overexpressing, sanguinarine-treated JM1 pre-B lymphoblastic cells displayed neither apoptosis nor BCD morphologies. sanguinarine 32-44 coiled-coil domain containing 22 Homo sapiens 288-291