PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
35176976-12	2022	Mechanistically, SAG decreased the protein stability of glutathione peroxide 4 (GPX4) through E3 ligase STUB1-mediated ubiquitination and degradation of endogenous GPX4.	sanguinarine	17-20	glutathione peroxidase 4	Homo sapiens	80-84	
35176976-12	2022	Mechanistically, SAG decreased the protein stability of glutathione peroxide 4 (GPX4) through E3 ligase STUB1-mediated ubiquitination and degradation of endogenous GPX4.	sanguinarine	17-20	glutathione peroxidase 4	Homo sapiens	164-168	
35176976-13	2022	GPX4 overexpression restored the proliferation and invasion of NSCLC cells treated with SAG through inhibiting ferroptosis.	sanguinarine	88-91	glutathione peroxidase 4	Homo sapiens	0-4	
35176976-14	2022	CONCLUSIONS: SAG inhibits the growth and metastasis of NSCLC by regulating STUB1/GPX4-dependent ferroptosis.	sanguinarine	13-16	glutathione peroxidase 4	Homo sapiens	81-85