PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
5768869-4	1969	After being extensively washed, the enzyme acetylcholinesterase (AChase) was specifically reactivated by treatment with pyridine-2-aldoxime methiodide (2-PAM).	pralidoxime	120-150	peptidylglycine alpha-amidating monooxygenase	Mus musculus	154-157	
2872135-9	1986	Combinations of these agents with 2-pyridine aldoxime methochloride (2-PAM) (50 mg/kg) improved prophylactic action even further.	pralidoxime	34-67	peptidylglycine alpha-amidating monooxygenase	Mus musculus	71-74	
4092617-1	1985	The present study demonstrates that dose combinations of atropine sulfate and 2-pyridine aldoxime methylchloride (2-PAM), which do not produce any overt toxic effects on the behavior of mice or guinea pigs in a stable environment, elicit clonic-tonic convulsions and death when the animals are physically stressed by cold water swimming.	pralidoxime	78-112	peptidylglycine alpha-amidating monooxygenase	Mus musculus	116-119	
4181315-9	1969	The first involved reactivation of the phosphorylated AChase by pyridine-2-aldoxime methiodide (2-PAM), in conditions in which the reactivation of other enzymes would be insignificant.	pralidoxime	64-94	peptidylglycine alpha-amidating monooxygenase	Mus musculus	98-101	
13747325-1	1960	In experiments on mice treated with pralidoxime iodide (pyridine-2-aldoxime methiodide; PAM) and atropine, the cholinesterase activity in the brain was assayed after poisoning with very high doses of organophosphorous anticholinesterases.	pralidoxime	36-54	peptidylglycine alpha-amidating monooxygenase	Mus musculus	88-91	
28078916-1	2017	The study reports antidotal efficacy of three HNK [ bis quaternary 2-(hydroxyimino)-N-(pyridin-3yl) acetamide derivatives] and pralidoxime (2-PAM), against soman and tabun poisoning in Swiss albino mice.	pralidoxime	127-138	peptidylglycine alpha-amidating monooxygenase	Mus musculus	142-145	
26962110-5	2017	AChE reactivation efficacy of HNK series and pralidoxime (2-PAM) were determined by plotting shift of log IC50 doses.	pralidoxime	45-56	peptidylglycine alpha-amidating monooxygenase	Mus musculus	60-63	
25045830-10	2014	Finally, VX-induced caspase-3 or -9 activities were reduced with the addition of pralidoxime (2-PAM), one of the current therapeutics used against NA toxicity, and dizocilpine (MK-801).	pralidoxime	81-92	peptidylglycine alpha-amidating monooxygenase	Mus musculus	96-99