PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 5927092-0 1966 [Reactivation of phosphoryl cholinesterase in the cerebral cortex of rats following parenteral administration of pralidoxime (PAM-2) and toxogonine (LuH-6)]. pralidoxime 113-124 butyrylcholinesterase Rattus norvegicus 28-42 6761901-0 1982 The influence of obidoxime, diacetylmonoxime, pralidoxime, and two less hydrophilic derivatives of pralidoxime upon the cholinesterase inhibition and the pressor effect by paraoxon in the rat. pralidoxime 99-110 butyrylcholinesterase Rattus norvegicus 120-134 5962089-0 1966 Reactivation of paraoxon-inactivated cholinesterase in the rat cerebral cortex by pralidoxime chloride. pralidoxime 82-102 butyrylcholinesterase Rattus norvegicus 37-51 13618543-4 1958 Diacetylmonoxime, at an equimolar dose, produced only a slight increase in enzyme activity, and pyridine-2-aldoxime methiodide, the best reactivator in vitro, reactivated blood but not brain cholinesterase. pralidoxime 96-126 butyrylcholinesterase Rattus norvegicus 191-205 19839597-4 2009 This manuscript describes an alternative strategy where reactivation of the phosphorylated enzyme was exploited to enable measurement of both inhibited and baseline ChE activity (after reactivation by an oxime, i.e., pralidoxime iodide) in the same sample. pralidoxime 217-235 butyrylcholinesterase Rattus norvegicus 165-168 23220589-6 2013 The aim of the present study was to evaluate the efficacy of some ChE reactivators against OPC intoxication (tabun, paraoxon and dichlorvos) in in vitro experiments and to compare their activity to that known for some currently used oximes (obidoxime, HI-6, 2-PAM). pralidoxime 258-263 butyrylcholinesterase Rattus norvegicus 66-69 17304644-1 2007 There is a clear need for broad-spectrum cholinesterase reactivators (active against a multitude of organophosphorus ester enzyme inhibitors) with a higher efficacy than pralidoxime. pralidoxime 170-181 butyrylcholinesterase Rattus norvegicus 41-55