PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 34888674-8 2022 The NAA/Cr ratio was negatively correlated with BMI z-scores (r = -0.25, P = 0.03) and serum insulin (rho = -0.27, P = 0.04), C-peptide (rho = -0.26, P = 0.04), amylin (r = -0.27, P = 0.04), ghrelin (rho = -0.30, P = 0.02) and neuropeptide Y (r = -0.27, P = 0.04). N-acetylaspartate 4-7 insulin Homo sapiens 93-100 26575297-5 2016 Bipolar disorders complicated by insulin resistance/T2DM are associated with smaller hippocampal and cortical gray matter volumes and lower prefrontal N-acetyl aspartate (neuronal marker). N-acetylaspartate 151-169 insulin Homo sapiens 33-40 32715663-5 2020 Higher insulin resistance was associated with lower prefrontal NAA levels in the T2DM-O group (t = -2.21, P = 0.032) but not in the T2DM-N group (t = -0.72, P = 0.48). N-acetylaspartate 63-66 insulin Homo sapiens 7-14 32033248-1 2020 Because of a decreased sensitivity toward insulin, a key regulator of pyruvate dehydrogenase (PDH), Alzheimer"s patients have lower brain glucose utilization with reductions in Tricarboxylic Acid (TCA) cycle metabolites such as citrate, a precursor to n-acetyl-aspartate. N-acetylaspartate 252-270 insulin Homo sapiens 42-49 23596182-10 2013 Insulin infusion resulted in an increase in frontal NAA/Cr and NAA/H2O and frontal and temporal Glx/Cr and Glx/H2O and a decrease in frontal Cho/Cr and temporal Cho/H2O and myo-inositol/H2O (all P < 0.05, except temporal Glx/H2O, P = 0.054, NS) in the high-IS, but not in the low-IS, group. N-acetylaspartate 52-55 insulin Homo sapiens 0-7 23596182-10 2013 Insulin infusion resulted in an increase in frontal NAA/Cr and NAA/H2O and frontal and temporal Glx/Cr and Glx/H2O and a decrease in frontal Cho/Cr and temporal Cho/H2O and myo-inositol/H2O (all P < 0.05, except temporal Glx/H2O, P = 0.054, NS) in the high-IS, but not in the low-IS, group. N-acetylaspartate 63-66 insulin Homo sapiens 0-7 23596182-11 2013 Insulin sensitivity correlated positively with frontal NAA/Cr and NAA/H2O and temporal Glx/H2O and negatively with temporal myo-inositol/Cr and myo-inositol/H2O assessed during the second (1)H-MRS (all P < 0.05). N-acetylaspartate 55-58 insulin Homo sapiens 0-7 23596182-11 2013 Insulin sensitivity correlated positively with frontal NAA/Cr and NAA/H2O and temporal Glx/H2O and negatively with temporal myo-inositol/Cr and myo-inositol/H2O assessed during the second (1)H-MRS (all P < 0.05). N-acetylaspartate 66-69 insulin Homo sapiens 0-7