PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 26459214-1 2015 Glutamate carboxypeptidase II (GCPII) is a zinc metalloprotease on the surface of astrocytes which cleaves N-acetylaspartylglutamate to release N-acetylaspartate and glutamate. N-acetylaspartate 144-161 folate hydrolase 1 Homo sapiens 0-29 26459214-1 2015 Glutamate carboxypeptidase II (GCPII) is a zinc metalloprotease on the surface of astrocytes which cleaves N-acetylaspartylglutamate to release N-acetylaspartate and glutamate. N-acetylaspartate 144-161 folate hydrolase 1 Homo sapiens 31-36 23525278-1 2013 Glutamate carboxypeptidase II (GCPII) is an exopeptidase that catalyzes the hydrolysis of N-acetylated aspartate-glutamate (NAAG) to N-acetyl aspartate (NAA) and glutamate. N-acetylaspartate 133-151 folate hydrolase 1 Homo sapiens 0-29 23525278-1 2013 Glutamate carboxypeptidase II (GCPII) is an exopeptidase that catalyzes the hydrolysis of N-acetylated aspartate-glutamate (NAAG) to N-acetyl aspartate (NAA) and glutamate. N-acetylaspartate 133-151 folate hydrolase 1 Homo sapiens 31-36 23525278-1 2013 Glutamate carboxypeptidase II (GCPII) is an exopeptidase that catalyzes the hydrolysis of N-acetylated aspartate-glutamate (NAAG) to N-acetyl aspartate (NAA) and glutamate. N-acetylaspartate 124-127 folate hydrolase 1 Homo sapiens 0-29 23525278-1 2013 Glutamate carboxypeptidase II (GCPII) is an exopeptidase that catalyzes the hydrolysis of N-acetylated aspartate-glutamate (NAAG) to N-acetyl aspartate (NAA) and glutamate. N-acetylaspartate 124-127 folate hydrolase 1 Homo sapiens 31-36 22304714-6 2012 It is cleaved by a specific peptidase located on astrocytes, glutamate carboxypeptidase type II (GCP-II), to N-acetylaspartate (NAA) and glutamate. N-acetylaspartate 109-126 folate hydrolase 1 Homo sapiens 61-95 22124883-1 2012 Glutamate carboxypeptidase II (GCPII) catalyzes the hydrolysis of N-acetylaspartylglutamate into N-acetylaspartate and glutamate in the brain. N-acetylaspartate 97-114 folate hydrolase 1 Homo sapiens 0-29 22124883-1 2012 Glutamate carboxypeptidase II (GCPII) catalyzes the hydrolysis of N-acetylaspartylglutamate into N-acetylaspartate and glutamate in the brain. N-acetylaspartate 97-114 folate hydrolase 1 Homo sapiens 31-36 22304714-6 2012 It is cleaved by a specific peptidase located on astrocytes, glutamate carboxypeptidase type II (GCP-II), to N-acetylaspartate (NAA) and glutamate. N-acetylaspartate 109-126 folate hydrolase 1 Homo sapiens 97-103 22304714-6 2012 It is cleaved by a specific peptidase located on astrocytes, glutamate carboxypeptidase type II (GCP-II), to N-acetylaspartate (NAA) and glutamate. N-acetylaspartate 128-131 folate hydrolase 1 Homo sapiens 61-95 22304714-6 2012 It is cleaved by a specific peptidase located on astrocytes, glutamate carboxypeptidase type II (GCP-II), to N-acetylaspartate (NAA) and glutamate. N-acetylaspartate 128-131 folate hydrolase 1 Homo sapiens 97-103 22304717-1 2012 Glutamate carboxypeptidase II (GCPII, EC 3.4.17.21) is a zinc metallopeptidase that hydrolyzes N-acetylaspartylglutamate (NAAG) into N-acetylaspartate (NAA) and glutamate in the nervous system. N-acetylaspartate 133-150 folate hydrolase 1 Homo sapiens 0-29 22304717-1 2012 Glutamate carboxypeptidase II (GCPII, EC 3.4.17.21) is a zinc metallopeptidase that hydrolyzes N-acetylaspartylglutamate (NAAG) into N-acetylaspartate (NAA) and glutamate in the nervous system. N-acetylaspartate 133-150 folate hydrolase 1 Homo sapiens 31-36 22304717-1 2012 Glutamate carboxypeptidase II (GCPII, EC 3.4.17.21) is a zinc metallopeptidase that hydrolyzes N-acetylaspartylglutamate (NAAG) into N-acetylaspartate (NAA) and glutamate in the nervous system. N-acetylaspartate 122-125 folate hydrolase 1 Homo sapiens 0-29 22304717-1 2012 Glutamate carboxypeptidase II (GCPII, EC 3.4.17.21) is a zinc metallopeptidase that hydrolyzes N-acetylaspartylglutamate (NAAG) into N-acetylaspartate (NAA) and glutamate in the nervous system. N-acetylaspartate 122-125 folate hydrolase 1 Homo sapiens 31-36 7575102-4 1995 Moreover, NAAG is cleaved to glutamate and N-acetylaspartate by a specific peptidase, N-acetyl-alpha-linked acidic dipeptidase (NAALADase). N-acetylaspartate 43-60 folate hydrolase 1 Homo sapiens 86-126 19457086-5 2009 Interestingly, over-expression of Folh1 would be expected to result in accumulation of its enzymatic product N-acetyl-aspartate, an event known to be linked to Canavan disease, a human cerebral degenerative syndrome often involving blindness and hearing loss. N-acetylaspartate 109-127 folate hydrolase 1 Homo sapiens 34-39 16467855-1 2006 Membrane-bound glutamate carboxypeptidase II (GCPII) is a zinc metalloenzyme that catalyzes the hydrolysis of the neurotransmitter N-acetyl-L-aspartyl-L-glutamate (NAAG) to N-acetyl-L-aspartate and L-glutamate (which is itself a neurotransmitter). N-acetylaspartate 173-193 folate hydrolase 1 Homo sapiens 15-44 16467855-1 2006 Membrane-bound glutamate carboxypeptidase II (GCPII) is a zinc metalloenzyme that catalyzes the hydrolysis of the neurotransmitter N-acetyl-L-aspartyl-L-glutamate (NAAG) to N-acetyl-L-aspartate and L-glutamate (which is itself a neurotransmitter). N-acetylaspartate 173-193 folate hydrolase 1 Homo sapiens 46-51 15027864-1 2004 The neuropeptidase glutamate carboxypeptidase II (GCPII) hydrolyzes N-acetyl-L-aspartyl-L-glutamate (NAAG) to liberate N-acetylaspartate and glutamate. N-acetylaspartate 119-136 folate hydrolase 1 Homo sapiens 19-48 15027864-1 2004 The neuropeptidase glutamate carboxypeptidase II (GCPII) hydrolyzes N-acetyl-L-aspartyl-L-glutamate (NAAG) to liberate N-acetylaspartate and glutamate. N-acetylaspartate 119-136 folate hydrolase 1 Homo sapiens 50-55 12917384-2 2004 For this purpose, we made use of 2-(3-mercaptopropyl)pentanedioic acid (2-MPPA), an inhibitor of glutamate carboxypeptidase II [GCP II; also known as N-acetylated alpha-linked acidic dipeptidase (NAALADase)], the enzyme that hydrolyzes NAAG into N-acetylaspartate and glutamate. N-acetylaspartate 246-263 folate hydrolase 1 Homo sapiens 97-126 12917384-2 2004 For this purpose, we made use of 2-(3-mercaptopropyl)pentanedioic acid (2-MPPA), an inhibitor of glutamate carboxypeptidase II [GCP II; also known as N-acetylated alpha-linked acidic dipeptidase (NAALADase)], the enzyme that hydrolyzes NAAG into N-acetylaspartate and glutamate. N-acetylaspartate 246-263 folate hydrolase 1 Homo sapiens 128-134 12826236-3 2003 N-acetylated-alpha-linked acidic dipeptidase (NAALADase; also termed glutamate carboxypeptidase II) yields N-acetyl aspartate (NAA) and glutamate. N-acetylaspartate 107-125 folate hydrolase 1 Homo sapiens 69-98 12826236-3 2003 N-acetylated-alpha-linked acidic dipeptidase (NAALADase; also termed glutamate carboxypeptidase II) yields N-acetyl aspartate (NAA) and glutamate. N-acetylaspartate 46-49 folate hydrolase 1 Homo sapiens 69-98 11525768-1 2001 N-acetylated-alpha-linked-acidic-dipeptidase (NAALADase or glutamate carboxypeptidase II) cleaves the neuropeptide N-acetyl-aspartyl-glutamate (NAAG) to glutamate and N-acetyl-aspartate (NAA). N-acetylaspartate 167-185 folate hydrolase 1 Homo sapiens 46-55 11525768-1 2001 N-acetylated-alpha-linked-acidic-dipeptidase (NAALADase or glutamate carboxypeptidase II) cleaves the neuropeptide N-acetyl-aspartyl-glutamate (NAAG) to glutamate and N-acetyl-aspartate (NAA). N-acetylaspartate 167-185 folate hydrolase 1 Homo sapiens 59-88 11525768-1 2001 N-acetylated-alpha-linked-acidic-dipeptidase (NAALADase or glutamate carboxypeptidase II) cleaves the neuropeptide N-acetyl-aspartyl-glutamate (NAAG) to glutamate and N-acetyl-aspartate (NAA). N-acetylaspartate 46-49 folate hydrolase 1 Homo sapiens 59-88 11375762-3 2001 N-acetylated-a-linked acidic dipeptidase (NAALADase, EC 3.4.17.21) is responsible for the hydrolysis of NAAG into N-acetylaspartate (NAA) and glutamate. N-acetylaspartate 114-131 folate hydrolase 1 Homo sapiens 0-40 11375762-3 2001 N-acetylated-a-linked acidic dipeptidase (NAALADase, EC 3.4.17.21) is responsible for the hydrolysis of NAAG into N-acetylaspartate (NAA) and glutamate. N-acetylaspartate 114-131 folate hydrolase 1 Homo sapiens 42-51 11375762-3 2001 N-acetylated-a-linked acidic dipeptidase (NAALADase, EC 3.4.17.21) is responsible for the hydrolysis of NAAG into N-acetylaspartate (NAA) and glutamate. N-acetylaspartate 42-45 folate hydrolase 1 Homo sapiens 0-40 9882712-1 1999 Glutamate carboxypeptidase II (GCP II) catalyzes the extracellular hydrolysis of the neuromodulator N-acetyl-aspartylglutamate to N-acetyl-aspartate and glutamate. N-acetylaspartate 130-148 folate hydrolase 1 Homo sapiens 0-29 9882712-1 1999 Glutamate carboxypeptidase II (GCP II) catalyzes the extracellular hydrolysis of the neuromodulator N-acetyl-aspartylglutamate to N-acetyl-aspartate and glutamate. N-acetylaspartate 130-148 folate hydrolase 1 Homo sapiens 31-37 15136672-5 2004 The coding sequence of the gene coding for glutamate carboxypeptidase II, which converts NAAG to N-acetylaspartate (NAA) and glutamate, was entirely sequenced but revealed no mutations. N-acetylaspartate 97-114 folate hydrolase 1 Homo sapiens 43-72 15136672-5 2004 The coding sequence of the gene coding for glutamate carboxypeptidase II, which converts NAAG to N-acetylaspartate (NAA) and glutamate, was entirely sequenced but revealed no mutations. N-acetylaspartate 89-92 folate hydrolase 1 Homo sapiens 43-72 12413472-1 2002 Glutamate carboxypeptidase II (GCPII or prostate-specific membrane antigen or NAALADase) is an enzyme that catalyzes the hydrolysis of the neuropeptide N-acetylaspartylglutamate (NAAG) to N-acetylaspartate (NAA) and glutamate (G). N-acetylaspartate 188-205 folate hydrolase 1 Homo sapiens 0-29 12413472-1 2002 Glutamate carboxypeptidase II (GCPII or prostate-specific membrane antigen or NAALADase) is an enzyme that catalyzes the hydrolysis of the neuropeptide N-acetylaspartylglutamate (NAAG) to N-acetylaspartate (NAA) and glutamate (G). N-acetylaspartate 188-205 folate hydrolase 1 Homo sapiens 31-36 12413472-1 2002 Glutamate carboxypeptidase II (GCPII or prostate-specific membrane antigen or NAALADase) is an enzyme that catalyzes the hydrolysis of the neuropeptide N-acetylaspartylglutamate (NAAG) to N-acetylaspartate (NAA) and glutamate (G). N-acetylaspartate 188-205 folate hydrolase 1 Homo sapiens 78-87 12413472-1 2002 Glutamate carboxypeptidase II (GCPII or prostate-specific membrane antigen or NAALADase) is an enzyme that catalyzes the hydrolysis of the neuropeptide N-acetylaspartylglutamate (NAAG) to N-acetylaspartate (NAA) and glutamate (G). N-acetylaspartate 78-81 folate hydrolase 1 Homo sapiens 0-29 12413472-1 2002 Glutamate carboxypeptidase II (GCPII or prostate-specific membrane antigen or NAALADase) is an enzyme that catalyzes the hydrolysis of the neuropeptide N-acetylaspartylglutamate (NAAG) to N-acetylaspartate (NAA) and glutamate (G). N-acetylaspartate 78-81 folate hydrolase 1 Homo sapiens 31-36 9361299-3 1997 NAAG is catabolized to N-acetylaspartate and glutamate primarily by glutamate carboxypeptidase II, which is expressed on the extracellular surface of astrocytes. N-acetylaspartate 23-40 folate hydrolase 1 Homo sapiens 68-97 7575102-4 1995 Moreover, NAAG is cleaved to glutamate and N-acetylaspartate by a specific peptidase, N-acetyl-alpha-linked acidic dipeptidase (NAALADase). N-acetylaspartate 43-60 folate hydrolase 1 Homo sapiens 128-137 8532851-2 1995 NAA is synthesized by L-aspartate N-acetyl transferase or by cleavage from N-acetyl aspartyl glutamate by N-acylated alpha-linked L-amino dipeptidase (NAALADase); and it is catabolized to acetate and aspartate by N-acetyl aspartate amino hydrolase (amino acylase II). N-acetylaspartate 0-3 folate hydrolase 1 Homo sapiens 151-160 30970252-3 2019 We found that NAAG is more abundant in higher grade cancers and is a source of glutamate in cancers expressing glutamate carboxypeptidase II (GCPII), the enzyme that hydrolyzes NAAG to glutamate and N-acetyl-aspartate (NAA). N-acetylaspartate 199-217 folate hydrolase 1 Homo sapiens 111-140 30970252-3 2019 We found that NAAG is more abundant in higher grade cancers and is a source of glutamate in cancers expressing glutamate carboxypeptidase II (GCPII), the enzyme that hydrolyzes NAAG to glutamate and N-acetyl-aspartate (NAA). N-acetylaspartate 199-217 folate hydrolase 1 Homo sapiens 142-147 30970252-3 2019 We found that NAAG is more abundant in higher grade cancers and is a source of glutamate in cancers expressing glutamate carboxypeptidase II (GCPII), the enzyme that hydrolyzes NAAG to glutamate and N-acetyl-aspartate (NAA). N-acetylaspartate 14-17 folate hydrolase 1 Homo sapiens 111-140 30970252-3 2019 We found that NAAG is more abundant in higher grade cancers and is a source of glutamate in cancers expressing glutamate carboxypeptidase II (GCPII), the enzyme that hydrolyzes NAAG to glutamate and N-acetyl-aspartate (NAA). N-acetylaspartate 14-17 folate hydrolase 1 Homo sapiens 142-147