PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
6166344-4	1981	In contrast, the release of cortical [(3)H]-noradrenaline and [(14)C]-acetylcholine caused by the alkaloid was greatly diminished in Ca-free medium.5 The veratridine but not the K-evoked release of [(3)H]-GABA was abolished when the external Na concentration [Na](o) was reduced to zero and by tetrodotoxin (TTX) (0.2 muM).	Alkaloids	98-106	latexin	Homo sapiens	318-321	
32134650-5	2020	Alkaloids 1-4 were evaluated for their potential to inhibit AGE formation and showed inhibition of 62.9%, 83.3%, 26.1%, and 98.2% (150 muM), respectively.	Alkaloids	0-9	latexin	Homo sapiens	135-138	
29156968-4	2018	As a result, alkaloids 1, 2, and 4 exhibited cytotoxicities against all the five tested tumor cell lines with IC50 value of less than 20 muM.	Alkaloids	13-22	latexin	Homo sapiens	137-140	
30243778-4	2018	As a result, alkaloids 1 and 2 exhibited cytotoxic activities (IC50 values <20 muM) against all tested tumor cell lines and significant antibacterial properties (MIC values from 0.12 to 0.26 mM).	Alkaloids	13-22	latexin	Homo sapiens	82-85	
28393571-4	2017	Consequently, alkaloids 2 and 3 exhibited cytotoxic activities for all tested tumor cell lines with IC50 values from 9.2 to 13.0 muM.	Alkaloids	14-23	latexin	Homo sapiens	129-132	
28333079-4	2017	Monanchomycalin B is the most active among all published marine alkaloids (EC50 6.02, 2.84, and 3.25 muM for TRPV1, TRPV2, and TRPV3, correspondingly).	Alkaloids	64-73	latexin	Homo sapiens	101-104	
25687604-3	2015	Alkaloids 1 and 2 are voaphylline-vobasinyl type bisindole alkaloids, a structural type previously unknown, while 3-6 exhibited cytotoxicity against three human cancer cell lines HeLa, MCF-7, and SW480 with IC50 values ranging from 1.42 to 11.35 muM.	Alkaloids	0-9	latexin	Homo sapiens	246-249	
26222678-4	2016	The alkaloids 1, 5, 12, 13 and the phenolic 2, 8, 11 tested compounds exhibited non-selective moderate cytotoxic activity with IC50 8.7-15.9 muM whereas compounds 3, 4, 6, 7, 9 and 10 showed low activity.	Alkaloids	4-13	latexin	Homo sapiens	141-144	
25863351-4	2015	Promising results have been showed by alkaloids californidine (IC50=55.6+-3.5 muM), dihydrosanquinarine (IC50=99.1+-7.6 muM), corypalmine (IC50=128.0+-10.5 muM) and N-methyllaurotetanine (IC50=135.0+-11.7 muM).	Alkaloids	38-47	latexin	Homo sapiens	78-81	
23368752-2	2013	We report syntheses of amphimedosides A-C that feature a stereoselective oxyamine neoglycosylation and found that these alkaloids display modest cytotoxicity toward seven diverse human cancer cell lines, exhibiting IC(50) values ranging from 3.0 muM to greater than 100 muM.	Alkaloids	120-129	latexin	Homo sapiens	246-249	
23368752-2	2013	We report syntheses of amphimedosides A-C that feature a stereoselective oxyamine neoglycosylation and found that these alkaloids display modest cytotoxicity toward seven diverse human cancer cell lines, exhibiting IC(50) values ranging from 3.0 muM to greater than 100 muM.	Alkaloids	120-129	latexin	Homo sapiens	270-273	
22968712-2	2013	A competitive binding assay using CHO membranes showed that GM (IC(50) = 0.034 muM) more strongly inhibited the binding of the radioligand [(3)H] LSD to 5-HT(7) receptor than the other alkaloids, suggesting that GM is bound to 5-HT(7) receptor.	Alkaloids	185-194	latexin	Homo sapiens	79-82	
22406451-6	2012	The results showed that these alkaloids inhibited cell proliferation with IC(50) values between 14muM and 22muM.	Alkaloids	30-39	latexin	Homo sapiens	98-101