PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
32955004-11	2021	Interestingly, the therapeutic impact of alkaloids against blood glucose pathogenesis is mediated through a variety of signaling cascades and pathways, via inhibiting or stimulating a diversity of systems such as inhibition of alpha-glucosidase enzyme, blockade of PTP-1B, deactivation of DPP-IV, increasing insulin sensitivity and modulating the oxidative stress.	Alkaloids	41-50	protein tyrosine phosphatase non-receptor type 1	Homo sapiens	265-271	
30108832-2	2017	The screen resulted in the identification of the natural product alkaloids, berberine and palmatine as well as alpha-tocopheryl succinate (alpha-TOS) as potential inhibitors of PTP1B.	Alkaloids	65-74	protein tyrosine phosphatase non-receptor type 1	Homo sapiens	177-182	
19336898-6	2009	Our findings should encourage screening of other natural alkaloids for possible anti-h-PTP 1B activities.	Alkaloids	57-66	protein tyrosine phosphatase non-receptor type 1	Homo sapiens	87-93