PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 20706796-5 2011 In the occurrence of cytotoxic effects of atisine-type alkaloids, replacement by an acyl group at both C-11 and C-15 resulted in the enhancement of activity of the parent alkaloids compared to that from having hydroxy groups at this position, and the presence of a hydroxy group at the C-6 position was required for the cytotoxic effects. Alkaloids 55-64 aldo-keto reductase family 1 member C4 Homo sapiens 103-107 20706796-5 2011 In the occurrence of cytotoxic effects of atisine-type alkaloids, replacement by an acyl group at both C-11 and C-15 resulted in the enhancement of activity of the parent alkaloids compared to that from having hydroxy groups at this position, and the presence of a hydroxy group at the C-6 position was required for the cytotoxic effects. Alkaloids 171-180 aldo-keto reductase family 1 member C4 Homo sapiens 103-107