PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
21369818-0	2011	Fenofibric acid prevents retinal pigment epithelium disruption induced by interleukin-1beta by suppressing AMP-activated protein kinase (AMPK) activation.	fenofibric acid	0-15	interleukin 1 beta	Homo sapiens	74-91	
21369818-8	2011	RESULTS: Treatment of ARPE-19 cells with fenofibric acid significantly reduced the increment of permeability and the breakdown of the ARPE-19 cell monolayer induced by D-glucose, 25 mmol/l, and IL-1beta, 10 ng/ml, in a dose-dependent manner.	fenofibric acid	41-56	interleukin 1 beta	Homo sapiens	194-202	
21369818-10	2011	Fenofibric acid prevented the activation of AMPK induced by IL-1beta and the hyperpermeability induced by IL-1beta was blocked by silencing AMPK.	fenofibric acid	0-15	interleukin 1 beta	Homo sapiens	60-68	
21369818-10	2011	Fenofibric acid prevented the activation of AMPK induced by IL-1beta and the hyperpermeability induced by IL-1beta was blocked by silencing AMPK.	fenofibric acid	0-15	interleukin 1 beta	Homo sapiens	106-114	
21369818-11	2011	CONCLUSIONS/INTERPRETATION: Disruption of RPE induced by IL-1beta is prevented by fenofibric acid through its ability to suppress AMPK activation.	fenofibric acid	82-97	interleukin 1 beta	Homo sapiens	57-65