PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
18485727-0	2008	Binding of 8-anilino-1-naphthalenesulfonate to lecithin:cholesterol acyltransferase studied by fluorescence techniques.	8-anilino-1-naphthalenesulfonic acid	11-43	lecithin-cholesterol acyltransferase	Homo sapiens	47-83	
18485727-1	2008	The solvatochromic fluorescent probe 8-anilino-1-naphthalenesulfonate (ANS) has been used to study the hydrophobicity and conformational dynamics of lecithin:cholesterol acyltransferase (LCAT).	8-anilino-1-naphthalenesulfonic acid	37-69	lecithin-cholesterol acyltransferase	Homo sapiens	149-185	
18485727-1	2008	The solvatochromic fluorescent probe 8-anilino-1-naphthalenesulfonate (ANS) has been used to study the hydrophobicity and conformational dynamics of lecithin:cholesterol acyltransferase (LCAT).	8-anilino-1-naphthalenesulfonic acid	37-69	lecithin-cholesterol acyltransferase	Homo sapiens	187-191	
18485727-1	2008	The solvatochromic fluorescent probe 8-anilino-1-naphthalenesulfonate (ANS) has been used to study the hydrophobicity and conformational dynamics of lecithin:cholesterol acyltransferase (LCAT).	8-anilino-1-naphthalenesulfonic acid	71-74	lecithin-cholesterol acyltransferase	Homo sapiens	149-185	
18485727-1	2008	The solvatochromic fluorescent probe 8-anilino-1-naphthalenesulfonate (ANS) has been used to study the hydrophobicity and conformational dynamics of lecithin:cholesterol acyltransferase (LCAT).	8-anilino-1-naphthalenesulfonic acid	71-74	lecithin-cholesterol acyltransferase	Homo sapiens	187-191	
18485727-2	2008	The ANS to LCAT binding constant was estimated from titrations with ANS, keeping a constant concentration of LCAT (2 microM).	8-anilino-1-naphthalenesulfonic acid	4-7	lecithin-cholesterol acyltransferase	Homo sapiens	11-15	
18485727-2	2008	The ANS to LCAT binding constant was estimated from titrations with ANS, keeping a constant concentration of LCAT (2 microM).	8-anilino-1-naphthalenesulfonic acid	4-7	lecithin-cholesterol acyltransferase	Homo sapiens	109-113	
18485727-2	2008	The ANS to LCAT binding constant was estimated from titrations with ANS, keeping a constant concentration of LCAT (2 microM).	8-anilino-1-naphthalenesulfonic acid	68-71	lecithin-cholesterol acyltransferase	Homo sapiens	11-15	
18485727-5	2008	In the later case, not only ANS but also tryptophan (Trp) residues of LCAT is being excited.	8-anilino-1-naphthalenesulfonic acid	28-31	lecithin-cholesterol acyltransferase	Homo sapiens	70-74	
18485727-9	2008	The lifetime of ANS bound to LCAT was above 16 ns which is characteristic for it being in a hydrophobic environment.	8-anilino-1-naphthalenesulfonic acid	16-19	lecithin-cholesterol acyltransferase	Homo sapiens	29-33	
18485727-10	2008	The ANS labeled LCAT fluorescence anisotropy decay revealed the correlation time of 42 ns with a weak residual motion of 2.8 ns.	8-anilino-1-naphthalenesulfonic acid	4-7	lecithin-cholesterol acyltransferase	Homo sapiens	16-20	
18485727-11	2008	These characteristics of ANS labeled LCAT fluorescence show that ANS is an excellent probe to study conformational changes of LCAT protein and its interactions with other macromolecules.	8-anilino-1-naphthalenesulfonic acid	25-28	lecithin-cholesterol acyltransferase	Homo sapiens	37-41	
18485727-11	2008	These characteristics of ANS labeled LCAT fluorescence show that ANS is an excellent probe to study conformational changes of LCAT protein and its interactions with other macromolecules.	8-anilino-1-naphthalenesulfonic acid	25-28	lecithin-cholesterol acyltransferase	Homo sapiens	126-130	
18485727-11	2008	These characteristics of ANS labeled LCAT fluorescence show that ANS is an excellent probe to study conformational changes of LCAT protein and its interactions with other macromolecules.	8-anilino-1-naphthalenesulfonic acid	65-68	lecithin-cholesterol acyltransferase	Homo sapiens	37-41	
18485727-11	2008	These characteristics of ANS labeled LCAT fluorescence show that ANS is an excellent probe to study conformational changes of LCAT protein and its interactions with other macromolecules.	8-anilino-1-naphthalenesulfonic acid	65-68	lecithin-cholesterol acyltransferase	Homo sapiens	126-130