PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
17670769-4	2008	METHODS: Rats subjected to renal I/R were either treated with daily intraperitoneal injection of selective JAK2 inhibitor tyrphostin AG490 (10 mg/kg) or vehicle alone starting 4 h before, immediately after or until 3 h after I/R.	Tyrphostins	122-132	Janus kinase 2	Rattus norvegicus	107-111	
17008107-9	2007	Both the enhancement of STAT5 phosphorylation and the neuroprotection rendered by EPO were blocked by Tyrphostin, a selective inhibitor for Janus kinase 2, which is an upstream kinase of STAT5.	Tyrphostins	102-112	Janus kinase 2	Rattus norvegicus	140-154	
12504822-4	2003	We further compared the effects of in vivo blockade of RAS by the AT(1) receptor (AT(1)R) blocker losartan with the in vivo blockade of JAK-STAT pathway by the specific JAK2 blocker tyrphostin AG490 on certain aspects of early post-MI remodeling.	Tyrphostins	182-192	Janus kinase 2	Rattus norvegicus	169-173	
12055089-5	2002	In addition, we also found that this increase in proliferation can be inhibited by incubation of the cells in tyrphostin AG 490, a specific inhibitor of Janus-activated kinase (JAK) 2 activity.	Tyrphostins	110-120	Janus kinase 2	Rattus norvegicus	177-180	
11457752-6	2001	Treatment of the hearts with losartan (4.5 micromol/L), an AT(1) blocker, or with tyrphostin AG490 (5 micromol/L), an inhibitor of JAK 2 phosphorylation, results in loss of the STAT/ANG promoter binding activity and an upregulated level of ANG mRNA.	Tyrphostins	82-92	Janus kinase 2	Rattus norvegicus	131-136	
11457752-7	2001	Hearts treated with the JAK 2 inhibitor tyrphostin AG490 showed a reduction in myocardial infarct size and in number of cardiomyocytes undergoing apoptosis.	Tyrphostins	40-50	Janus kinase 2	Rattus norvegicus	24-29	
10499497-17	1999	PRL inhibition of IL-6 expression was totally reversed by tyrphostin AG490, a JAK2 inhibitor.	Tyrphostins	58-68	Janus kinase 2	Rattus norvegicus	78-82