PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
20659490-8	2010	SM exposure also resulted in increased expression of markers of inflammation including cyclooxygenase-2 (COX-2), tumor necrosis factor-alpha (TNFalpha), inducible nitric oxide synthase (iNOS), and matrix metalloproteinase-9 (MMP-9), each of which has been implicated in pulmonary toxicity.	Mustard Gas	0-2	tumor necrosis factor	Rattus norvegicus	113-140	
20659490-8	2010	SM exposure also resulted in increased expression of markers of inflammation including cyclooxygenase-2 (COX-2), tumor necrosis factor-alpha (TNFalpha), inducible nitric oxide synthase (iNOS), and matrix metalloproteinase-9 (MMP-9), each of which has been implicated in pulmonary toxicity.	Mustard Gas	0-2	tumor necrosis factor	Rattus norvegicus	142-150	
22465472-6	2012	In rats, SM induced a burst of pro-inflammatory cytokines/chemokines within 72 h, including IL-1beta, TNF-alpha, IL-2, IL-6, CCL2, CCL3, CCL11, and CXCL1 that was associated with neutrophilic infiltration into the lung.	Mustard Gas	9-11	tumor necrosis factor	Rattus norvegicus	102-111	
34390737-0	2021	Pulmonary injury and oxidative stress in rats induced by inhaled sulfur mustard is ameliorated by anti-tumor necrosis factor-alpha antibody.	Mustard Gas	65-79	tumor necrosis factor	Rattus norvegicus	103-130	
34390737-8	2021	Anti-TNFalpha antibody was found to blunt SM-induced peribronchial edema, perivascular inflammation and alveolar plasma protein and inflammatory cell accumulation in the lung; this was associated with reduced expression of PCNA in histologic sections and decreases in BAL levels of fibrinogen.	Mustard Gas	42-44	tumor necrosis factor	Rattus norvegicus	5-13	
34390737-9	2021	SM-induced increases in inflammatory proteins including soluble receptor for glycation end products, its ligand, high mobility group box-1, and matrix metalloproteinase-9 were also reduced by anti-TNFalpha antibody administration, along with increases in numbers of lung macrophages expressing TNFalpha, cyclooxygenase-2 and inducible nitric oxide synthase.	Mustard Gas	0-2	tumor necrosis factor	Rattus norvegicus	197-205	
34390737-9	2021	SM-induced increases in inflammatory proteins including soluble receptor for glycation end products, its ligand, high mobility group box-1, and matrix metalloproteinase-9 were also reduced by anti-TNFalpha antibody administration, along with increases in numbers of lung macrophages expressing TNFalpha, cyclooxygenase-2 and inducible nitric oxide synthase.	Mustard Gas	0-2	tumor necrosis factor	Rattus norvegicus	294-302	
34390737-11	2021	Together, these data suggest that inhibiting TNFalpha may represent an efficacious approach to mitigating acute lung injury, inflammatory macrophage activation, and oxidative stress induced by inhaled sulfur mustard.	Mustard Gas	201-215	tumor necrosis factor	Rattus norvegicus	45-53