PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
22444276-13	2012	These results demonstrate that HBO preconditioning has directly beneficial effects on ODG-exposed cortical neurons by the activation of PPAR gamma subsequent to the production of 15d-PGJ(2), which in turn increases the downstream antioxidant enzymatic activities.	15d-pgj	179-186	peroxisome proliferator-activated receptor gamma	Rattus norvegicus	136-146	
19891980-7	2010	ICV administration of structurally dissimilar PPARgamma antagonists (either GW9662 or BADGE) reversed the anti-inflammatory and anti-hyperalgesic actions of both rosiglitazone and 15d-PGJ(2).	15d-pgj	180-187	peroxisome proliferator-activated receptor gamma	Rattus norvegicus	46-55	
19647045-3	2009	This antinociceptive effect is dependent on peroxisome proliferator-activated receptors-gamma (PPAR-gamma) since pre-treatment with GW9662 (PPAR-gamma receptor antagonist) blocked the antinociceptive effect of 15d-PGJ(2) in the TMJ.	15d-pgj	210-217	peroxisome proliferator-activated receptor gamma	Rattus norvegicus	95-105	
19942298-6	2010	These results suggest that PPAR-gamma agonists, 15d-PGJ(2) and pioglitazone, had the anti-inflammatory effects.	15d-pgj	48-55	peroxisome proliferator-activated receptor gamma	Rattus norvegicus	27-37	
19647045-3	2009	This antinociceptive effect is dependent on peroxisome proliferator-activated receptors-gamma (PPAR-gamma) since pre-treatment with GW9662 (PPAR-gamma receptor antagonist) blocked the antinociceptive effect of 15d-PGJ(2) in the TMJ.	15d-pgj	210-217	peroxisome proliferator-activated receptor gamma	Rattus norvegicus	140-150	
19647045-9	2009	Taken together, these results demonstrate that 15d-PGJ(2) has a potential peripheral antinociceptive and anti-inflammatory effect in the TMJ via PPAR-gamma activation.	15d-pgj	47-54	peroxisome proliferator-activated receptor gamma	Rattus norvegicus	145-155	
19647045-11	2009	The pharmacological properties of the peripheral administration of 15d-PGJ(2) highlight the potential use of this PPAR-gamma agonist on TMJ inflammatory pain conditions.	15d-pgj	67-74	peroxisome proliferator-activated receptor gamma	Rattus norvegicus	114-124	
20107546-5	2009	The upregulatory effect of 15d-PGJ(2) in SHR VSMCs was mediated through PPARgamma, and dependent on NF-kappaB activation and ERK phosphorylation.	15d-pgj	27-34	peroxisome proliferator-activated receptor gamma	Rattus norvegicus	72-81	
20107546-8	2009	CONCLUSION: Our results indicate that the upregulatory effect of 15d-PGJ(2) on LPS-induced IL-8/CXCL8 expression in SHR VSMCs is mediated through the PPARgamma and ERK pathway, and may be related to NAD(P)H oxidase activity.	15d-pgj	65-72	peroxisome proliferator-activated receptor gamma	Rattus norvegicus	150-159	
18079203-6	2008	Pharmacological inhibition (predominantly through beta-adrenergic receptor) of the stress-released catecholamines in the central nervous system regulates 15d-PGJ(2) and PGE(2) synthesis, by reducing COX-2 overexpression, and reduces PPARgamma activation.	15d-pgj	154-161	peroxisome proliferator-activated receptor gamma	Rattus norvegicus	233-242	
15304320-9	2004	15d-PGJ(2) exhibited the same effect in chondrocytes overexpressing mutated PPARgamma protein.	15d-pgj	0-7	peroxisome proliferator-activated receptor gamma	Rattus norvegicus	76-85	
15720836-16	2004	CONCLUSIONS: 15d-PGJ(2) significantly inhibited the severity of acute gastric mucosal injury induced by I/R in rats through PPAR-gamma-dependent mechanisms.	15d-pgj	13-20	peroxisome proliferator-activated receptor gamma	Rattus norvegicus	124-134	
10903334-8	2000	These findings suggest that PPAR-gamma may be an important immunoinflammatory mediator and its ligands, especially 15d-PGJ(2), may be useful in the treatment of RA.	15d-pgj	115-122	peroxisome proliferator-activated receptor gamma	Rattus norvegicus	28-38	
17484875-9	2007	Pretreatment with PPARgamma agonists 15d-PGJ(2) and rosiglitazone prevented colonic inflammation and barrier dysfunction as well as the decrease of IgA production induced after acute stress; PPARgamma specific antagonist T0070907 reverted these effects.	15d-pgj	37-44	peroxisome proliferator-activated receptor gamma	Rattus norvegicus	18-27	
17484875-9	2007	Pretreatment with PPARgamma agonists 15d-PGJ(2) and rosiglitazone prevented colonic inflammation and barrier dysfunction as well as the decrease of IgA production induced after acute stress; PPARgamma specific antagonist T0070907 reverted these effects.	15d-pgj	37-44	peroxisome proliferator-activated receptor gamma	Rattus norvegicus	191-200	
16725118-4	2006	Intraventricular injection of 15d-Delta(12,14)-prostaglandin J(2) (15d-PGJ(2)), a proposed endogenous PPARgamma agonist, into the ischemic rat brains significantly increased the PPARgamma-DNA-binding activity and reduced infarction volume at 24 h after reperfusion.	15d-pgj	67-74	peroxisome proliferator-activated receptor gamma	Rattus norvegicus	102-111	
16725118-4	2006	Intraventricular injection of 15d-Delta(12,14)-prostaglandin J(2) (15d-PGJ(2)), a proposed endogenous PPARgamma agonist, into the ischemic rat brains significantly increased the PPARgamma-DNA-binding activity and reduced infarction volume at 24 h after reperfusion.	15d-pgj	67-74	peroxisome proliferator-activated receptor gamma	Rattus norvegicus	178-187