PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
24975445-0	2014	Amlodipine prevents adriamycin-induced toxicity in cultured rat mesangial cells by up-regulation of Smad6, Smad7 expression.	Amlodipine	0-10	SMAD family member 6	Rattus norvegicus	100-105	
24975445-6	2014	The aim of this study was to investigate effects of amlodipine on adriamycin-induced changes of lactate dehydrogenase (LDH) and expression of Smad6, 7 in rat mesangial cells.	Amlodipine	52-62	SMAD family member 6	Rattus norvegicus	142-147	
24975445-7	2014	Results showed that amlodipine (10(-8) to 10(-5)mol/l) significantly decreased LDH activity in rat mesangial cells when given in combination with TGF-beta1 (P<0.01); amlodipine (10(-7), 10(-6)mol/l) significantly increased Smad6, 7 mRNA and protein expression in cells treated with adriamycin and TGF-beta1 (P<0.01).	Amlodipine	20-30	SMAD family member 6	Rattus norvegicus	226-234	
24975445-8	2014	In conclusion, amlodipine protects against adriamycin-induced toxicity in rat mesangial cells by up-regulation of Smad6, 7 expressions.	Amlodipine	15-25	SMAD family member 6	Rattus norvegicus	114-119