PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 20197055-3 2010 Thus, deletion of p110alpha in liver results in markedly blunted insulin signaling with decreased generation of PIP(3) and loss of insulin activation of Akt, defects that could not be rescued by overexpression of p110beta. pip(3) 112-118 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Mus musculus 18-27 17371237-3 2007 Recruitment of the p85-p110 complex to receptors and adaptor proteins via the p85 SH2 (Src homology 2) domains alleviates this inhibition, leading to PI3K activation and production of PIP(3) (phosphatidylinositol 3,4,5-trisphosphate). pip(3) 184-190 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Mus musculus 23-27