PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 17535963-4 2007 In agreement with this model, depletion of Src homology 2 domain-containing inositol polyphosphate 5-phosphatase 2 (SHIP2) markedly potentiated NGF-induced Rac1/Cdc42 activation and PIP(3) accumulation and considerably increased the number and the length of neurites in phosphate and tensin homologue-depleted PC12 cells. pip(3) 182-188 inositol polyphosphate phosphatase-like 1 Rattus norvegicus 116-121 17535963-6 2007 We propose that the SHIP2-mediated negative feedback on PIP(3) coordinately works with the PI3-kinase-mediated positive feedback to form an initial protrusive pattern and, later, to punctuate the PIP(3) accumulation to maintain proper neurite outgrowth. pip(3) 56-62 inositol polyphosphate phosphatase-like 1 Rattus norvegicus 20-25 17535963-6 2007 We propose that the SHIP2-mediated negative feedback on PIP(3) coordinately works with the PI3-kinase-mediated positive feedback to form an initial protrusive pattern and, later, to punctuate the PIP(3) accumulation to maintain proper neurite outgrowth. pip(3) 196-202 inositol polyphosphate phosphatase-like 1 Rattus norvegicus 20-25