PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 10747990-4 2000 Amino acid substitutions in helix 5 within the RGS domain of RGS4 reduce binding affinity and inhibition by PIP(3) but do not affect inhibition of GAP activity by palmitoylation. pip(3) 108-114 regulator of G protein signaling 4 Homo sapiens 61-65 10747990-5 2000 Conversely, the GAP activity of a palmitoylation-resistant mutant RGS4 is inhibited by PIP(3). pip(3) 87-93 regulator of G protein signaling 4 Homo sapiens 66-70