PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 20498366-7 2010 However, the amplitude of the PIP(3) response after PKA inhibition was restored by a specific agonist to the cAMP-dependent guanine nucleotide exchange factor Epac. pip(3) 30-36 Rap guanine nucleotide exchange factor (GEF) 3 Mus musculus 159-163 20498366-8 2010 Suppression of cAMP formation with adenylyl cyclase inhibitors reduced already established PIP(3) oscillations in glucose-stimulated cells, and this effect was almost completely counteracted by the Epac agonist. pip(3) 91-97 Rap guanine nucleotide exchange factor (GEF) 3 Mus musculus 198-202