PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 20200318-9 2010 These changes were independent of impaired proliferation of muscle progenitor or satellite cells but were principally related to increased expression of PTEN, which reduced PIP(3) in muscle. pip(3) 173-179 phosphatase and tensin homolog Mus musculus 153-157 19454716-2 2009 PIP(3) is produced by PI3K and regulated by PTEN (phosphatase and tensin homolog deleted on chromosome 10) and SHIP lipid phosphatases. pip(3) 0-6 phosphatase and tensin homolog Mus musculus 44-48 17623817-3 2007 RESEARCH DESIGN AND METHODS: We evaluated the expression and activity of PTEN, the phosphatase converting PIP(3) to inactive phosphatidylinositol 4,5-bisphosphate, and studied how PTEN influences muscle protein in diabetic wild-type mice and in mice with partial deficiency of PTEN(+/-). pip(3) 106-112 phosphatase and tensin homolog Mus musculus 73-77 17371230-2 2007 The major substrate of PTEN is PIP(3) (phosphatidylinositol 3,4,5-trisphosphate) generated by the action of PI3Ks (phosphoinositide 3-kinases). pip(3) 31-37 phosphatase and tensin homolog Mus musculus 23-27