PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 23754155-0 2013 MAGI2 enhances the sensitivity of BEL-7404 human hepatocellular carcinoma cells to staurosporine-induced apoptosis by increasing PTEN stability. Staurosporine 83-96 phosphatase and tensin homolog Homo sapiens 129-133 16971513-5 2006 In addition, apoptosis of HeLa cells induced by staurosporine or serum-depletion was alleviated by the PICT-1 knockdown in the similar PTEN-dependent manner. Staurosporine 48-61 phosphatase and tensin homolog Homo sapiens 135-139 17169462-3 2007 We have recently demonstrated an implication of phosphatase and tensin homologue deleted on chromosome 10 (PTEN), a tumor suppressor, in ROS generation and neuronal apoptosis induced by staurosporine. Staurosporine 186-199 phosphatase and tensin homolog Homo sapiens 107-111 11965494-0 2002 PTEN augments staurosporine-induced apoptosis in PTEN-null Ishikawa cells by downregulating PI3K/Akt signaling pathway. Staurosporine 14-27 phosphatase and tensin homolog Homo sapiens 0-4 11965494-0 2002 PTEN augments staurosporine-induced apoptosis in PTEN-null Ishikawa cells by downregulating PI3K/Akt signaling pathway. Staurosporine 14-27 phosphatase and tensin homolog Homo sapiens 49-53 11965494-2 2002 We investigated the involvement of PTEN in staurosporine-induced apoptosis. Staurosporine 43-56 phosphatase and tensin homolog Homo sapiens 35-39 11965494-11 2002 Staurosporine reduced the levels of phospho-Akt/PKB and phospho-Bad (Ser-136) in all the cell lines, but the reduction was most significant in the PTEN-expressing clone. Staurosporine 0-13 phosphatase and tensin homolog Homo sapiens 147-151 11803475-6 2002 PTEN also sensitized cells to non-receptor mediated apoptosis induced by a kinase inhibitor staurosporine and chemotherapeutic agents mitoxantrone and etoposide. Staurosporine 92-105 phosphatase and tensin homolog Homo sapiens 0-4 11803475-12 2002 PTEN facilitated BID cleavage after treatment with low doses of staurosporine and mitoxantrone. Staurosporine 64-77 phosphatase and tensin homolog Homo sapiens 0-4 15968641-4 2005 Induction of PTEN by removal of doxycycline enhanced both capsase-3 and cell death with staurosporine, wortmannin, or C2-ceramide, whereas antisense PTEN had the reverse effect. Staurosporine 88-101 phosphatase and tensin homolog Homo sapiens 13-17