PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 9369952-6 1997 A PKC inhibitor, staurosporine (5 microM) likewise inhibited the BK-induced increase in endothelial cell permeability to albumin. Staurosporine 17-30 kininogen 1 Bos taurus 65-67 8220902-9 1993 Exposure of AG04762 cells for 10 min to staurosporine produced a concentration-dependent inhibition (IC50 = 107 +/- 14 nM) in bradykinin-stimulated prostacyclin release. Staurosporine 40-53 kininogen 1 Bos taurus 126-136 8433044-8 1993 In contrast, bradykinin- or ATP-induced phosphorus 32-labeled PA and [32P]-labeled PEt formation was only partially blocked (70% inhibition) by either staurosporine (10 mumol/L) or PKC down-regulation, suggesting that part of agonist-stimulated PLD activity may occur in the absence of PKC activation. Staurosporine 151-164 kininogen 1 Bos taurus 13-23 1446322-7 1992 In contrast, staurosporine (a putative inhibitor of protein kinase C) substantially inhibited the U46619 and bradykinin dependent release of 6-oxo-PGF1 alpha. Staurosporine 13-26 kininogen 1 Bos taurus 109-119 1665733-8 1991 Furthermore, staurosporine (100 nM) increased [Ca2+]i when added during the plateau phase of the increase in [Ca2+]i induced by thrombin or bradykinin. Staurosporine 13-26 kininogen 1 Bos taurus 140-150