PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 7510523-3 1994 The protein kinase A (PKA)-specific inhibitor, KT5720, also inhibited the IL-1-induced PGE2 production in MC3T3-E1 cells, as did staurosporine, a potent inhibitor of protein kinase C (PKC). Staurosporine 129-142 interleukin 1 complex Mus musculus 74-78 9328844-2 1997 Staurosporine and calphostin C, inhibitors of protein kinase C (PKC), significantly enhanced the IL-1-induced secretion of IL-6. Staurosporine 0-13 interleukin 1 complex Mus musculus 97-101 8407943-3 1993 Staurosporine abolished the enhanced phosphorylation in response to IL-1 for some of these proteins, suggesting that protein kinase C (PKC) was at least partially responsible. Staurosporine 0-13 interleukin 1 complex Mus musculus 68-72 8282136-10 1993 Similarly, staurosporin inhibited the IL-1-induced PGE2 production in MC in a dose dependent manner. Staurosporine 11-23 interleukin 1 complex Mus musculus 38-42 1282723-2 1992 The tumor necrosis factor-alpha- (TNF-alpha) and interleukin-1 (IL-1)-stimulated ICAM-1 expression in TEC is blocked with the PKC/PKA inhibitor staurosporine, and also with the PKC-selective inhibitor calphostin C. Staurosporine 144-157 interleukin 1 complex Mus musculus 49-68 2268359-5 1990 The enhancement of CRF-stimulated beta-endorphin release by IL-1 was also reduced in AtT-20 cells after depletion of protein kinase C, and after treatment with staurosporine. Staurosporine 160-173 interleukin 1 complex Mus musculus 60-64