PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
17634380-3	2007	Here, we show that, at baseline, CREB(alpha delta) mutant mice exhibited increased hippocampal cell proliferation and neurogenesis compared with wild-type (WT) controls, effects similar to those observed in WT mice after chronic desipramine (DMI) administration.	Desipramine	229-240	cAMP responsive element binding protein 1	Mus musculus	33-37	
27338163-0	2016	Desipramine improves depression-like behavior and working memory by up-regulating p-CREB in Alzheimer"s disease associated mice.	Desipramine	0-11	cAMP responsive element binding protein 1	Mus musculus	84-88	
27338163-8	2016	The neuroprotection of desipramine may be involved in the up-regulation of p-CREB level in the hippocampus of mice.	Desipramine	23-34	cAMP responsive element binding protein 1	Mus musculus	77-81	
17634380-3	2007	Here, we show that, at baseline, CREB(alpha delta) mutant mice exhibited increased hippocampal cell proliferation and neurogenesis compared with wild-type (WT) controls, effects similar to those observed in WT mice after chronic desipramine (DMI) administration.	Desipramine	242-245	cAMP responsive element binding protein 1	Mus musculus	33-37	
11943827-6	2002	Furthermore, the ability of DMI to suppress an acute corticosterone response after swim stress is maintained in CREB-deficient mice.	Desipramine	28-31	cAMP responsive element binding protein 1	Mus musculus	112-116	
11943827-7	2002	However, upregulation of a molecular target of CREB, BDNF, is abolished in the CREB-deficient mice after chronic administration of DMI.	Desipramine	131-134	cAMP responsive element binding protein 1	Mus musculus	47-51	
11943827-7	2002	However, upregulation of a molecular target of CREB, BDNF, is abolished in the CREB-deficient mice after chronic administration of DMI.	Desipramine	131-134	cAMP responsive element binding protein 1	Mus musculus	79-83