PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
25463972-5	2014	In this study, we determined the functional role of the leptin receptor (LepRb) in behavioral responses to the selective serotonergic antidepressant fluoxetine and the noradrenergic antidepressant desipramine.	Desipramine	197-208	leptin receptor	Mus musculus	73-78	
25463972-6	2014	While acute and chronic treatment with fluoxetine or desipramine in wild-type mice elicited antidepressant-like effects in the forced swim test, mice null for LepRb (db/db) displayed resistance to treatment with either fluoxetine or desipramine.	Desipramine	233-244	leptin receptor	Mus musculus	159-164	
25463972-9	2014	Deletion of LepRb specifically from hippocampal and cortical neurons resulted in fluoxetine insensitivity in the forced swim test and tail suspension test while leaving the response to desipramine intact.	Desipramine	185-196	leptin receptor	Mus musculus	12-17	
25463972-10	2014	These results suggest that functional LepRb is critically involved in regulating the antidepressant-like behavioral effects of both fluoxetine and desipramine.	Desipramine	147-158	leptin receptor	Mus musculus	38-43