PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
9084457-2	1997	At least three different P450s appear to be responsible for the N-demethylation of imipramine to desipramine in vivo: CYP1A2, CYP2C19, and CYP3A4.	Desipramine	97-108	cytochrome P450 family 1 subfamily A member 2	Homo sapiens	118-124	
15922009-3	2005	The different CYPs involved in IMI demethylation to the pharmacologically active metabolite desipramine (DES) were CYP2C19 > CYP1A2 > CYP3A4.	Desipramine	92-103	cytochrome P450 family 1 subfamily A member 2	Homo sapiens	128-134	
15922009-3	2005	The different CYPs involved in IMI demethylation to the pharmacologically active metabolite desipramine (DES) were CYP2C19 > CYP1A2 > CYP3A4.	Desipramine	105-108	cytochrome P450 family 1 subfamily A member 2	Homo sapiens	128-134	
14716709-6	2004	A study on the relative influence of CYP1A2 and 3A4 only revealed minor changes in the presence of desipramine.	Desipramine	99-110	cytochrome P450 family 1 subfamily A member 2	Homo sapiens	37-43