PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
22277074-3	2012	The results show that the 5-hydroxy-tetraindole 8 (SK228) has optimum antiproliferative activity against breast adenocarcinoma (MCF 7 and MDA-MB-231) cells and that this activity involves G(2)-phase arrest of the cell cycle with a distinctive increase in the expression of cyclin B1 and phospho-cdc2.	1,4-bis(di(5-hydroxy-1H-indol-3-yl)methyl)benzene	51-56	cyclin dependent kinase 1	Homo sapiens	295-299