PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
10328570-4	1999	The co-administration of sulfamethazine, which is known to be metabolized by a male-specific cytochrome P450 (CYP) isoform (CYP2C11), significantly decreased the CLp of acetohexamide in male Wistar-IM rats.	Acetohexamide	169-182	cytochrome P450, subfamily 2, polypeptide 11	Rattus norvegicus	124-131	
10328570-5	1999	Based on these results, it is reasonable to assume that the sex-dependent pharmacokinetics of acetohexamide observed in Wistar-IM rats is associated with the male-specific hydroxylation catalyzed by CYP2C11.	Acetohexamide	94-107	cytochrome P450, subfamily 2, polypeptide 11	Rattus norvegicus	199-206