PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
31954768-2	2020	Thus, protective effects of erythropoietin(EPO) on myelinization of oligodendrocytes and schwann cells respectively in CNS and PNS following MS induced by cuprizone (CPZ) administration in young female mice.	Cuprizone	155-164	erythropoietin	Mus musculus	43-46	
31954768-2	2020	Thus, protective effects of erythropoietin(EPO) on myelinization of oligodendrocytes and schwann cells respectively in CNS and PNS following MS induced by cuprizone (CPZ) administration in young female mice.	Cuprizone	166-169	erythropoietin	Mus musculus	43-46	
29498007-6	2018	Further, we measured the effects of EPO on preventing mitochondrial deficits in the cuprizone toxic demyelinating mouse model of MS. We found that EPO prevented cuprizone-mediated decreases in Hbb, complex III, and NAA.	Cuprizone	84-93	erythropoietin	Mus musculus	147-150	
29498007-6	2018	Further, we measured the effects of EPO on preventing mitochondrial deficits in the cuprizone toxic demyelinating mouse model of MS. We found that EPO prevented cuprizone-mediated decreases in Hbb, complex III, and NAA.	Cuprizone	161-170	erythropoietin	Mus musculus	36-39	
29498007-6	2018	Further, we measured the effects of EPO on preventing mitochondrial deficits in the cuprizone toxic demyelinating mouse model of MS. We found that EPO prevented cuprizone-mediated decreases in Hbb, complex III, and NAA.	Cuprizone	161-170	erythropoietin	Mus musculus	147-150	
29085580-0	2017	Protective effects of erythropoietin against cuprizone-induced oxidative stress and demyelination in the mouse corpus callosum.	Cuprizone	45-54	erythropoietin	Mus musculus	22-36	
29085580-2	2017	The aim of the present work is to investigate the protective effects of erythropoietin against cuprizone-induced oxidative stress.	Cuprizone	95-104	erythropoietin	Mus musculus	72-86	
29085580-7	2017	Biochemical analysis showed that oxidative stress induced by cuprizone was regulated by erythropoietin.	Cuprizone	61-70	erythropoietin	Mus musculus	88-102	
29085580-8	2017	Similarly, erythropoietin induced the expression of subunits of the respiratory chain complex over normal control values reflecting a mechanism to compensate cuprizone-mediated down-regulation of these genes.	Cuprizone	158-167	erythropoietin	Mus musculus	11-25	
29085580-9	2017	CONCLUSION: The data implicate that erythropoietin abolishes destructive cuprizone effects in the corpus callosum by decreasing oxidative stress and restoring mitochondrial respiratory enzyme activity.	Cuprizone	73-82	erythropoietin	Mus musculus	36-50	
22396019-8	2012	Likewise, ventricular enlargement after cuprizone, as documented by MRI, was less pronounced upon EPO.	Cuprizone	40-49	erythropoietin	Mus musculus	98-101	
22396019-10	2012	Histological analysis of the corpus callosum revealed attenuation by EPO of the cuprizone-induced increase in microglial numbers and amyloid precursor protein accumulations as a readout of inflammation and axonal degeneration.	Cuprizone	80-89	erythropoietin	Mus musculus	69-72	
22396019-11	2012	To conclude, EPO ameliorates neurological symptoms in the cuprizone model of demyelination, possibly by reduction of inflammation-associated axonal degeneration in white matter tracts.	Cuprizone	58-67	erythropoietin	Mus musculus	13-16