PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 34358632-0 2021 STAT3 activation in hippocampal neural stem cells and cognitive deficits in mice following short-term cuprizone exposure. Cuprizone 102-111 signal transducer and activator of transcription 3 Mus musculus 0-5 29864483-12 2018 In conclusion, linagliptin exerted a neuroprotective effect in mice with cuprizone-induced demyelination possibly by modulating AMPK/SIRT1 and JAK2/STAT3/NF-kappaB signalling pathways. Cuprizone 73-82 signal transducer and activator of transcription 3 Mus musculus 148-153 34358632-6 2021 We then examined whether short-term CPZ exposure might induce activation of signal transducer and activator of transcription 3 (STAT3), which plays a major role in cytokine receptor signaling. Cuprizone 36-39 signal transducer and activator of transcription 3 Mus musculus 76-126 34358632-6 2021 We then examined whether short-term CPZ exposure might induce activation of signal transducer and activator of transcription 3 (STAT3), which plays a major role in cytokine receptor signaling. Cuprizone 36-39 signal transducer and activator of transcription 3 Mus musculus 128-133 34358632-7 2021 The densities of phosphorylated STAT3-positive (pSTAT3+) NSCs were higher in CPZ-fed mice than in normal-fed mice, while those of pSTAT3+ NPCs/NGCs were very low in both groups. Cuprizone 77-80 signal transducer and activator of transcription 3 Mus musculus 32-37 34358632-9 2021 These findings suggest that short-term CPZ exposure inhibits differentiation of NSCs into NPCs via activation of STAT3, which may in part underlie cognitive deficits. Cuprizone 39-42 signal transducer and activator of transcription 3 Mus musculus 113-118