PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
24966333-9	2014	Consistent with the two-step activation mechanism, the mechanism-based pan-E1 inhibitor, adenosine 5"-sulfamate (ADS), reacted with the Uba5~Ufm1 thioester and formed a covalent, tight-binding Ufm1-ADS adduct in the active site of Uba5, which prevented further substrate binding or catalysis.	uba5	136-140	ubiquitin fold modifier 1	Homo sapiens	141-145	
24966333-9	2014	Consistent with the two-step activation mechanism, the mechanism-based pan-E1 inhibitor, adenosine 5"-sulfamate (ADS), reacted with the Uba5~Ufm1 thioester and formed a covalent, tight-binding Ufm1-ADS adduct in the active site of Uba5, which prevented further substrate binding or catalysis.	uba5	136-140	ubiquitin fold modifier 1	Homo sapiens	193-197