PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
16822479-6	2006	Here, we present data to show that both 4-OH and 4"-OH are critical for the ability of 4,4"-DHS to induce down-regulation of ERalpha and suggest that 4,4"-DHS provides a useful scaffold for development of novel ERalpha antagonists.	4-oh	40-44	estrogen receptor 1	Homo sapiens	125-132	
22915089-6	2013	The 4-OH and 4-OH-NDM metabolites of TOR and TAM bound to estrogen receptor (ER) subtypes with fourfold to 30-fold greater affinity were 35- to 187-fold more efficient at antagonizing ER transactivation and had antiestrogenic potency that was up to 360-fold greater than their parent drugs.	4-oh	4-8	estrogen receptor 1	Homo sapiens	58-75	
22915089-6	2013	The 4-OH and 4-OH-NDM metabolites of TOR and TAM bound to estrogen receptor (ER) subtypes with fourfold to 30-fold greater affinity were 35- to 187-fold more efficient at antagonizing ER transactivation and had antiestrogenic potency that was up to 360-fold greater than their parent drugs.	4-oh	4-8	estrogen receptor 1	Homo sapiens	77-79	
22915089-6	2013	The 4-OH and 4-OH-NDM metabolites of TOR and TAM bound to estrogen receptor (ER) subtypes with fourfold to 30-fold greater affinity were 35- to 187-fold more efficient at antagonizing ER transactivation and had antiestrogenic potency that was up to 360-fold greater than their parent drugs.	4-oh	4-8	estrogen receptor 1	Homo sapiens	184-186