PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
27995497-6	2017	Mechanically, salinomycin-induced cell growth inhibition against human glioma was mainly achieved by induction of G1-phase arrest via triggering reactive oxide species (ROS)-mediated DNA damage, as convinced by the activation of histone, p53, p21 and p27.	salinomycin	14-25	H3 histone pseudogene 16	Homo sapiens	243-246	
21573958-4	2012	Sal treatment also reduced p21 levels in radiation-treated cells.	salinomycin	0-3	H3 histone pseudogene 16	Homo sapiens	27-30	
21573958-5	2012	Considering that Sal sensitizes doxorubicin (DOX)- or etoposide (ETO)-treated cancer cells by causing DNA damage and reducing p21 expression, the results from our study suggest that the mechanism underlying Sal sensitization is conserved in both chemo- and radiation-treated cells.	salinomycin	17-20	H3 histone pseudogene 16	Homo sapiens	126-129	
21573958-5	2012	Considering that Sal sensitizes doxorubicin (DOX)- or etoposide (ETO)-treated cancer cells by causing DNA damage and reducing p21 expression, the results from our study suggest that the mechanism underlying Sal sensitization is conserved in both chemo- and radiation-treated cells.	salinomycin	207-210	H3 histone pseudogene 16	Homo sapiens	126-129	
23352703-0	2013	Salinomycin induces apoptosis and senescence in breast cancer: upregulation of p21, downregulation of survivin and histone H3 and H4 hyperacetylation.	salinomycin	0-11	H3 histone pseudogene 16	Homo sapiens	79-82	
23352703-10	2013	Interestingly, treatment with low concentrations of Salinomycin induced a transient G1 arrest at earlier time point and G2 arrest at later point and senescence associated with enlarged cellmorphology, upregulation of p21 protein, increase in histone H3 and H4 hyperacetylation and expression of SA-beta-Gal activity.	salinomycin	52-63	H3 histone pseudogene 16	Homo sapiens	217-220	
20973777-0	2011	Salinomycin sensitizes cancer cells to the effects of doxorubicin and etoposide treatment by increasing DNA damage and reducing p21 protein.	salinomycin	0-11	H3 histone pseudogene 16	Homo sapiens	128-131	
20973777-9	2011	The level of anti-apoptotic p21 protein was increased by DOX or ETO but decreased by Sal, which increased proteasome activity.	salinomycin	85-88	H3 histone pseudogene 16	Homo sapiens	28-31	
20973777-11	2011	Overall, we demonstrated that the ability of Sal to sensitize cancer cells to the effects of DOX or ETO is associated with an increase in DNA damage and a decrease in anti-apoptotic protein p21 levels.	salinomycin	45-48	H3 histone pseudogene 16	Homo sapiens	190-193