PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
27765904-0	2016	Identification of DNA-PKcs as a primary resistance factor of salinomycin in osteosarcoma cells.	salinomycin	61-72	protein kinase, DNA-activated, catalytic subunit	Homo sapiens	18-26	
27765904-4	2016	Here we characterized DNA-dependent protein kinase catalytic subunit (DNA-PKcs) as a primary salinomycin resistance factor in OS cells.	salinomycin	93-104	protein kinase, DNA-activated, catalytic subunit	Homo sapiens	22-68	
27765904-4	2016	Here we characterized DNA-dependent protein kinase catalytic subunit (DNA-PKcs) as a primary salinomycin resistance factor in OS cells.	salinomycin	93-104	protein kinase, DNA-activated, catalytic subunit	Homo sapiens	70-78	
27765904-5	2016	DNA-PKcs inhibitors (NU7026, NU7441 and LY294002) or DNA-PKcs shRNA knockdown dramatically potentiated salinomycin-induced death and apoptosis of OS cells (U2OS and MG-63 lines).	salinomycin	103-114	protein kinase, DNA-activated, catalytic subunit	Homo sapiens	0-8	
27765904-5	2016	DNA-PKcs inhibitors (NU7026, NU7441 and LY294002) or DNA-PKcs shRNA knockdown dramatically potentiated salinomycin-induced death and apoptosis of OS cells (U2OS and MG-63 lines).	salinomycin	103-114	protein kinase, DNA-activated, catalytic subunit	Homo sapiens	53-61	
27765904-7	2016	Reversely, over-expression of DNA-PKcs in OS cells inhibited salinomycin"s lethality.	salinomycin	61-72	protein kinase, DNA-activated, catalytic subunit	Homo sapiens	30-38	
27765904-8	2016	For the mechanism study, we show that DNA-PKcs is required for salinomycin-induced pro-survival autophagy activation.	salinomycin	63-74	protein kinase, DNA-activated, catalytic subunit	Homo sapiens	38-46	
27765904-12	2016	Together, these results suggest that DNA-PKcs could be a primary resistance factor of salinomycin in OS cells.	salinomycin	86-97	protein kinase, DNA-activated, catalytic subunit	Homo sapiens	37-45	
27765904-13	2016	DNA-PKcs inhibition or silence may thus significantly increase salinomycin"s sensitivity in OS cells.	salinomycin	63-74	protein kinase, DNA-activated, catalytic subunit	Homo sapiens	0-8